Ridel ER 500 mg (Tablet (Extended Release))

Indications

• Reduction of elevated TC
• Reduction of elevated LDL-C
• Reduction of elevated Apo B levels
• Reduction of elevated TG levels
• Increase HDL-C levels
• Treatment of primary hypercholesterolemia
• Treatment of mixed dyslipidemia
• Reduction of risk of recurrent nonfatal myocardial infarction
• Treatment of very high serum triglyceride levels
• Adjunctive therapy for cardiovascular disease

Pharmacology

• Preparation of Nicotinic acid
• Lowers VLDL levels
• Lowers LDL levels
• Lowers total cholesterol levels
• Lowers triglyceride levels
• Raises HDL levels

Dosage & Administration

• Initial dose of 500 mg tablet at bedtime
• Maintenance dose of 1000-2000 mg once daily at bedtime
• Maximum daily dosage not to exceed 2000 mg
• Directed by registered physician

Interaction

• Potentiation of effects of ganglionic blocking agents
• Potentiation of effects of vasoactive drugs
• Metabolic clearance affected by concomitant aspirin
• Binding to bile acid-binding resins

Contraindications

• Hypersensitivity to Niacin or any component
• Significant or unexplained hepatic dysfunction
• Active peptic ulcer disease
• Arterial bleeding

Side Effects

• Flushing
• Itching
• Pruritis
• Nausea
• GI upset
• Jaundice
• Hypotension
• Tachycardia
• Increased serum blood glucose levels
• Increased uric acid levels
• Myalgia

Pregnancy & Lactation

• Not recommended for use due to lack of information

Precautions & Warnings

• Attempt to control hyperlipidemia with diet and exercise
• Observation for patients with past history of jaundice, hepatobiliary disease, or peptic ulcer
• Frequent monitoring of liver function tests and blood glucose levels
• Observation for dose-related rise in glucose intolerance in diabetic patients
• Observation in patients with unstable angina or in the acute phase of MI
• Caution for use in patients predisposed to gout
• Monitoring of phosphorus levels in patients at risk

Overdose Effects

• Nausea
• Dizziness
• Itching
• Vomiting
• Upset stomach
• Flushing

Storage Conditions

• Cool and dry place
• Protected from light and moisture
• Keep out of reach of children

Related Brands

• Niapid 500 mg (Tablet (Extended Release)) - drug-international-ltd