Restovit Plus (Capsule)

Indications

• Treatment of vitamin B-complex and vitamin C deficiencies
• Decreased intake due to restricted or unbalanced diet
• Reduced availability during treatment with antimicrobials
• Increased requirements due to elevated metabolic rate
• Micronutrient deficiencies during pregnancy or lactation

Composition

• Ascorbic Acid BP 175.0 mg
• Calcium D-Pantothenate BP 25.0 mg
• Cyanocobalamin BP 5 mcg
• Folic Acid BP 500 mcg
• Thiamine Mononitrate USP 50.0 mg
• Riboflavin BP 25.0 mg
• Pyridoxine Hydrochloride BP 10.0 mg
• Nicotinamide BP 100.0 mg

Pharmacology

• Vitamin B-Complex and Vitamin C function as cofactors of various enzymes
• Thiamine acts as a cofactor in the decarboxylation of keto acids
• Riboflavin plays a vital role in cellular respiratory reactions
• Pyridoxine takes part in decarboxylation and interconversion of amino acids
• Vitamin B12 is required for synthesis of DNA and maturation of RBCs
• Nicotinamide plays a vital role in cellular respiration
• Calcium Pantothenate functions as a cofactor for enzymes involved in transfer of acetyl groups
• Folic acid takes part in reactions involved in the synthesis of nucleotides
• Ascorbic acid takes part in biochemical reactions involving oxidation and in conversion of folic acid to folinic acid

Dosage & Administration

One capsule daily or as advised by the physician.

Interaction

• Folic acid may lower the serum concentration of phenytoin
• Pyridoxine can reduce the effect of levodopa

Contraindications

Hypersensitivity to any of the ingredients of this preparation

Side Effects

• Allergic reactions may occur in patients hypersensitive to any component
• Rare reports of anaphylactoid reactions following repeated injection
• Flushing, itching or burning of the skin may occur in patients susceptible to the effects of nicotinamide

Pregnancy & Lactation

Reports on safe administration of water-soluble vitamins during pregnancy

Precautions & Warnings

• Accompanied by specific therapy for the primary illness
• Treatment should be continued only until the deficiency is corrected
• Pyridoxine may reduce the therapeutic effects of levodopa in Parkinson's disease
• Riboflavin may color the urine yellow
• False positive result for sugar by Benedict's test due to the presence of ascorbic acid

Therapeutic Class

Specific combined vitamin preparations

Storage Conditions

Store in a cool and dry place, away from light and children

Related Brands

• Alvit-B Gold (Capsule) - albion-laboratories-limited
• Opsovit C (Capsule) - opsonin-pharma-ltd