Donor 6 mg+200 mg+50 mg (Tablet)

Indications

• Prevention of coronary heart diseases
• Prevention of certain types of cancer
• Aging prevention
• Prevention of free radical damage caused by excessive exercise
• Prevention of free radical damage caused by illness
• Prevention of free radical damage caused by certain medications
• Prevention of free radical damage caused by air pollution
• Prevention of free radical damage caused by smoke
• Prevention of free radical damage caused by radiation
• Prevention of free radical damage caused by pesticides
• Quenching of singlet oxygen by β carotene
• Deactivation of free radicals by vitamin C
• White blood cell activity increase by vitamin C
• Biochemistry of antibodies influenced by vitamin C
• Prostaglandin E1 affected by vitamin C
• B and T lymphocytes regulated by vitamin C
• Interferon influenced by vitamin C
• Scavenging of free radicals in the blood by vitamin E
• Protection against ill effects of smog and smoke by vitamin E
• Protection of vitamin A by vitamin E
• Conversion of beta carotene to vitamin A
• Biochemical functions of retinol
• Role in retina, growth, tissue differentiation, and immunological response by retinol
• Anti-cancer activity of retinol
• Powerful reducing agent property of vitamin C
• Scurvy prevention by vitamin C
• Cofactor in numerous biological processes by vitamin C
• Vitamin C and molecular oxygen essential for biochemical processes
• Synthesis of adrenal steroid hormones by vitamin C
• Defense against infection by vitamin C
• Importance for functioning of T-lymphocyte and leukocyte by vitamin C
• Anti-inflammatory activity of vitamin C
• Protection of cells against oxidation by vitamin C
• Increased iron absorption by high doses of ascorbic acid
• Defense against oxidative stress and lipid peroxidation by vitamin E
• Mopping up of peroxide radicals by tocopherol
• Restoration of steady-state situation by tocopherol
• Importance of vitamin E in most cell membranes
• Supply of reduced hydrogen to tocopherol by ascorbic acid
• Absorbtion decrease by combination with cholestyramine
• Absorption decrease by combination with colestipol
• Absorption decrease by combination with neomycin
• Reduced circulating vitamin C levels during prolonged administration of oral contraceptives containing estrogen
• Reduced circulating vitamin C levels during prolonged administration of tetracycline
• Reduced circulating vitamin C levels during prolonged administration of aspirin
• Enhancement of anticoagulant activity of anticoagulant drugs by vitamin E
• Impairment of intestinal absorption of vitamins A and K by high doses of vitamin E
• Contraindication in patients with hypersensitivity to any components
• Development of hypercarotenosis by large ingestion of carotenoids
• Gastrointestinal tract upset by large doses of vitamin C
• Renal stone formation by large doses of vitamin C
• Diarrhea caused by doses over 800 mg of vitamin E
• Abdominal pain or cramps caused by doses over 800 mg of vitamin E
• Fatigue caused by doses over 800 mg of vitamin E
• Reduced resistance to bacterial infection caused by doses over 800 mg of vitamin E
• Transiently raised blood pressure caused by doses over 800 mg of vitamin E
• No teratogenic effects of β carotene in humans
• No teratogenic effects of vitamin C in humans
• No teratogenic effects of vitamin E in humans
• Caution exercised in prescribing to pregnant women
• Caution exercised for heavy smokers and alcoholics when using β carotene
• Caution exercised for patients with hyperoxaluria when using vitamin C
• Caution exercised for patients taking anticoagulant drugs when using vitamin E

Pharmacology

• Conversion of beta carotene to vitamin A when required
• Biochemical functions of retinol
• Role in retinol on retina, growth, tissue differentiation, and immunological response
• Anti-cancer activity of retinol
• Powerful reducing agent property of vitamin C
• Scurvy prevention by vitamin C
• Cofactor in numerous biological processes by vitamin C
• Essential role of vitamin C and molecular oxygen in biochemical processes
• Synthesis of adrenal steroid hormones by vitamin C
• Defense against infection by vitamin C
• Importance for functioning of T-lymphocyte and leukocyte by vitamin C
• Anti-inflammatory activity of vitamin C
• Protection of cells against oxidation by vitamin C
• Increased iron absorption by high doses of ascorbic acid
• Defense against oxidative stress and lipid peroxidation by vitamin E
• Mopping up of peroxide radicals by tocopherol
• Restoration of steady-state situation by tocopherol
• Importance of vitamin E in most cell membranes
• Supply of reduced hydrogen to tocopherol by ascorbic acid

Dosage & Administration

• Oral administration
• Adult dose of 1 tablet daily
• Physician-prescribed dosage

Interaction

• Decreased absorption of β carotene with cholestyramine
• Decreased absorption of β carotene with colestipol
• Decreased absorption of β carotene with neomycin
• Reduced circulating vitamin C levels with oral contraceptives containing estrogen
• Reduced circulating vitamin C levels with tetracycline
• Reduced circulating vitamin C levels with aspirin
• Enhancement of anticoagulant activity with vitamin E
• Impairment of intestinal absorption of vitamins A and K with high doses of vitamin E

Contraindications

• Hypersensitivity to any components

Side Effects

• Hypercarotenosis with large ingestion of carotenoids
• Gastrointestinal tract upset with large doses of vitamin C
• Renal stone formation with large doses of vitamin C
• Diarrhea with doses over 800 mg of vitamin E
• Abdominal pain or cramps with doses over 800 mg of vitamin E
• Fatigue with doses over 800 mg of vitamin E
• Reduced resistance to bacterial infection with doses over 800 mg of vitamin E
• Transiently raised blood pressure with doses over 800 mg of vitamin E

Pregnancy & Lactation

• No teratogenic effects of β carotene in humans
• No teratogenic effects of vitamin C in humans
• No teratogenic effects of vitamin E in humans
• Caution exercised in prescribing to pregnant women

Precautions & Warnings

• Harm to heavy smokers and alcoholics by β carotene
• Caution exercised for patients with hyperoxaluria when using vitamin C
• Caution exercised for patients taking anticoagulant drugs when using vitamin E

Therapeutic Class

• Anti-oxidant Multivitamin preparations

Storage Conditions

• Dry place
• Below 30˚C

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