Acerux 200 mg (Tablet)
Unit Price: ৳ 14.05 (3 x 10: ৳ 421.50)
Strip Price: ৳ 140.50
Medicine Details
| Category | Details |
|---|---|
| Generic | Acyclovir oral |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Treatment of viral infections due to Herpes simplex virus
- Treatment of Varicella zoster virus infections
- Prophylaxis of Herpes simplex infections in immunocompromised patients
- Treatment of Herpes simplex virus infections of the skin and mucous membranes including initial and recurrent genital herpes and herpes labialis
Pharmacology
Aciclovir is a synthetic purine derivative that interferes with DNA synthesis and inhibits viral replication in cells infected with herpes virus.
Dosage & Administration
- Treatment of initial herpes simplex: 200 mg 5 times daily usually for 5 days
- Prevention of recurrence of herpes simplex: 200 mg 4 times daily or 400 mg twice daily possibly reduced to 200 mg 2 or 3 times daily and interrupted every 6-12 months
- Prophylactic treatment of herpes simplex in the immunocompromised patients: 200 to 400 mg 4 times daily
- Treatment of chicken pox: 800 mg 4 times daily for 5 days for adults and children over 40 kg
- Treatment of herpes zoster (Shingles): 800 mg 5 times daily for 7 days
- Treatment of initial rectal (Proctitis) herpes infections: 400 mg 5 times daily for 10 days or until clinical resolution occurs
- Renal Impairment: Dose reduction recommended for severe renal impairment
Interaction
Probenecid reduces Aciclovir excretion and increases plasma concentration and risk of toxicity
Contraindications
Hypersensitivity to Aciclovir
Side Effects
- Rash
- Gastrointestinal disturbance
- Rise in bilirubin and liver-related enzymes
- Increase in blood urea and creatinine
- Decrease in hematological indices
- Headache
- Neurological reaction
- Fatigue
Pregnancy & Lactation
Pregnancy category B; caution when administered to nursing mothers
Precautions & Warnings
Administer with caution in patients with renal impairment and adjust doses according to creatinine clearance; monitor neutrophil count at least twice weekly in neonates
Therapeutic Class
Herpes simplex & Varicella-zoster virus infections
Storage Conditions
Should be stored below 25°C and protected from light and moisture; Keep out of the reach of children