Acerux 400 mg (Tablet)

Unit Price: ৳ 22.00 (2 x 10: ৳ 440.00)
Strip Price: ৳ 220.00

Medicine Details

Title

  • Aciclovir Tablet

Categories

  • Antiviral Medication
  • Herpes Treatment
  • Infection Management

Description

  • Aciclovir is indicated for the treatment of viral infections due to Herpes simplex virus (type I & II) and Varicella zoster virus (herpes zoster & chicken pox). It is also used for the treatment of Herpes simplex virus infections of the skin and mucous membranes including initial and recurrent genital herpes and herpes labialis. In addition, it is indicated for the prophylaxis of Herpes simplex infections in immunocompromised patients.

Formulation

  • Tablet

Packaging

  • Bottle
  • Blister Pack

Color Options

  • White

Dosage

  • 200mg
  • 400mg
  • 800mg

Dosage Schedule

  • 5 times daily for 5 days
  • 4 times daily
  • 2 times daily
  • As directed by a registered physician

Age-specific Dosage

  • Adult dose
  • Children under 2 years: Half of the adult dose
  • Children over 2 years: Adult dose

Treatment Duration

  • 5 days
  • 7 days
  • 10 days
  • Longer if new lesions appear

Route of Administration

  • Oral

Pharmacology

  • Synthetic purine derivative
  • Interferes with DNA synthesis
  • Inhibits viral replication
  • Converted to Aciclovir Triphosphate
  • Peak plasma concentrations within 1.5-2 hours after oral administration
  • Widely distributed into body tissues and fluids
  • Excreted through the kidney

Interaction

  • Probenecid reduces Aciclovir excretion

Contraindications

  • Hypersensitivity to Aciclovir

Side Effects

  • Rash
  • Gastrointestinal disturbance
  • Rise in bilirubin and liver-related enzymes
  • Increase in blood urea and creatinine
  • Decrease in hematological indices
  • Headache
  • Neurological reaction
  • Fatigue

Pregnancy & Lactation

  • Pregnancy category B
  • Caution when administered to a nursing mother

Precautions & Warnings

  • Administered with caution in patients with renal impairment
  • Doses should be adjusted according to creatinine clearance
  • Monitor neutrophil count at least twice weekly in neonates

Therapeutic Class

  • Antiviral Agent

Storage Conditions

  • Store below 25°C
  • Protect from light and moisture
  • Keep out of the reach of children

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