Tienum 50 mg (Tablet)

Indications

• Reduces muscle spasm of intestine, biliary system, bladder, and uterus
• Symptomatic treatment of pain related to functional disorders of the digestive tract and biliary system
• Treatment of spasm and pain in urological and gynecological diseases

Pharmacology

• Tiemonium Methylsulphate is a competitive antagonist of acetylcholine and histamine
• Strengthens calcium bond with membrane phospholipids and proteins
• Inhibits intracellular contractile protein of visceral cell, causing inhibition of visceral spasm and pain

Dosage & Administration

• Adult dose: 2-6 tablets or 3-9 teaspoonfuls syrup daily in divided doses
• Children dose: 3 ml/kg or 6 mg/kg body weight daily in divided doses
• Injection dose: 1 Tiemonium Methylsulphate Injection 3 times daily through IV or IM route
• Suppository dose: 20 mg Tiemonium Methylsulphate suppository two or three times daily

Interaction

• Not to be used with other drugs without prior consult of a registered physician

Contraindications

• Not to be used in urethroprostatic disorder involving a risk of urine retention
• Contraindicated in patients at risk of angle closure glaucoma

Side Effects

• Risk of hypotension and tachycardia in certain individuals

Pregnancy & Lactation

• No teratogenic effects in animal studies
• Prudence recommended for nursing mothers
• No reported problems with normal use

Precautions & Warnings

• Caution for patients with disorders of the prostate, chronic bronchitis, coronary insufficiency, ambient hyperthermia, renal & hepatic insufficiency
• Risks of visual disturbances impacting driving or machine use

Use in Special Populations

• Safety and effectiveness not established in pediatric patients
• Efficacy and safety maintained with increasing age in geriatric patients

Overdose Effects

• No available data regarding overdose of Tienum tablet

Therapeutic Class

• Anticholinergics

Storage Conditions

• Keep in a dry place, away from light and heat
• Keep out of the reach of children

Common Questions about Tienum 50 mg Tablet

• An antispasmodic drug that reduces muscle spasm of the intestine, biliary system, bladder, and uterus
• Used for the treatment of pain in the digestive tract, biliary system, urological and gynecological diseases

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