Apocal-DM (Tablet)

Unit Price: ৳ 5.00 (1 x 15: ৳ 75.00)

Medicine Details

Indications

  • Prevention and treatment of osteoporosis
  • Maintaining strong bone growth
  • Proper functioning of heart, muscle and nerves
  • Nutritional supplement
  • Bone development and regeneration
  • Pregnancy & lactation
  • Deficiency state of Calcium, Vitamin D3, Magnesium, Zinc, Copper, Manganese & Boron

Composition

  • Calcium Carbonate BP equivalent to 600 mg elemental Calcium
  • Vitamin D3 BP (as Cholecalciferol) 200 IU
  • Magnesium Oxide BP equivalent to 40 mg Magnesium
  • Manganese Sulfate Monohydrate BP equivalent to 1.8 mg Manganese
  • Cupric Oxide equivalent to 1 mg Copper
  • Boron Citrate equivalent to 250 mcg Boron
  • Zinc Oxide BP equivalent to 7.5 mg Zinc

Pharmacology

  • Importance of nutrition in preventing osteoporosis
  • Role of Calcium, Magnesium & Vitamin D3 in bone health
  • Effects of micronutrients like Copper, Manganese, Zinc & Boron on bone health
  • Nutrient deficiency in patients with osteoporosis

Dosage & Administration

  • Adult dosage: 1 film-coated tablet twice daily
  • Best taken with or just after main meals with a full glass of water
  • Children 3-7 years: 1 effervescent tablet daily
  • Children 7 years and older: 1 to 2 effervescent tablets daily

Interaction

  • Risk of hypercalcemia with thiazide diuretics
  • Effects of certain foods on calcium absorption
  • Concomitant treatment with phenytoin or barbiturates
  • Effects of glucocorticoids on Vitamin D3
  • Interactions with digitalis, cardiac glycosides and calcium
  • Reduced absorption of thyroxin, bisphosphonates, antibiotics, and iron with calcium salts

Contraindications

  • Absolute contraindications related to hypercalcaemia and severe renal failure
  • Relative contraindications related to osteoporosis due to prolonged immobilization and renal stones

Side Effects

  • Mild gastro-intestinal disturbances
  • Occasional skin rash from vitamin-D3 supplements
  • Long term treatment effects at high doses

Pregnancy & Lactation

  • Increased requirements for calcium and vitamin-D3 during pregnancy and lactation
  • Hypercalcaemia effects on newborns
  • Passage of vitamin-D3 and metabolites into breast milk

Precautions & Warnings

  • Supervision for patients with mild to moderate renal failure or mild hypercalciuria
  • Periodic checks of plasma and urinary calcium levels
  • Urinary calcium excretion measurements for patients with history of renal stones
  • Monitoring serum and urinary calcium levels during long term treatment
  • Allowances for calcium and vitamin D3 supplements from other sources

Overdose Effects

  • Symptoms such as nausea, vomiting, drowsiness, dry mouth, loss of appetite, metallic taste, stomach cramps, diarrhea, headache & constipation

Therapeutic Class

  • Specific mineral & vitamin combined preparations

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

Related Brands