Cadmin Plus (Tablet)

Unit Price: ৳ 4.04 (1 x 30: ৳ 121.20)
Strip Price: ৳ 121.20

Medicine Details

Indications

  • Prevention and treatment of osteoporosis
  • Maintaining strong bone growth
  • Proper functioning of heart, muscle, and nerves
  • Nutritional supplement
  • Bone development and regeneration
  • Pregnancy & lactation support
  • Deficiency state of Calcium, Vitamin D3, Magnesium, Zinc, Copper, Manganese & Boron

Composition

  • 600 mg elemental Calcium per film-coated tablet
  • 200 IU Vitamin D3 per film-coated tablet
  • 40 mg Magnesium per film-coated tablet
  • 1.8 mg Manganese per film-coated tablet
  • 1 mg Copper per film-coated tablet
  • 250 mcg Boron per film-coated tablet
  • 7.5 mg Zinc per film-coated tablet
  • Calcium Carbonate BP equivalent to 600 mg elemental Calcium per effervescent tablet
  • Vitamin D3 BP (as Cholecalciferol) 400 IU per effervescent tablet
  • Magnesium Oxide BP equivalent to 40 mg Magnesium per effervescent tablet
  • Manganese Sulfate Monohydrate BP equivalent to 1.8 mg Manganese per effervescent tablet
  • Cupric Oxide equivalent to 1 mg Copper per effervescent tablet
  • Boron Citrate equivalent to 250 mcg Boron per effervescent tablet
  • Zinc Oxide BP equivalent to 7.5 mg Zinc per effervescent tablet

Pharmacology

  • Importance of Calcium, Magnesium, & Vitamin D3 for bone health
  • Role of Copper, Manganese, Zinc, & Boron in bone health
  • Macronutrients for bone
  • Vitamin D3's role in Calcium absorption

Dosage & Administration

  • Adult dosage: 1 film-coated tablet twice daily
  • Preferrable administration with or just after meals and a full glass of water
  • Dosage for children 3-7 years: 1 effervescent tablet daily
  • Dosage for children 7 years and older: 1 to 2 effervescent tablets daily

Interaction

  • Concurrent use with thiazide diuretics
  • Hypocalcaemia in digitalized patients
  • Effect on calcium absorption with certain foods
  • Effect of phenytoin or barbiturates on Vitamin D3
  • Effect of glucocorticoids on Vitamin D3
  • Interaction with phenytoin or barbiturates
  • Potential interaction with glucocorticoids
  • Interaction with digitalis and other cardiac glycosides
  • Reduced absorption of thyroxin, bisphosphonates, sodium fluoride, quinolone or tetracycline antibiotics, or iron by calcium salts

Contraindications

  • Hypercalcaemia resulting from myeloma, bone metastasis, or other malignant bone disease
  • Sarcoidosis
  • Primary hyperparathyroidism
  • Vitamin-D3 overdosage
  • Severe renal failure
  • Hypersensitivity to any tablet ingredient
  • Relative contraindications: osteoporosis due to prolonged immobilisation, renal stones, severe hypercalciuria

Side Effects

  • Mild gastrointestinal disturbances
  • Constipation
  • Flatulence
  • Nausea
  • Gastric pain
  • Diarrhea
  • Occasional skin rash following Vitamin-D3 administration
  • Hypercalciuria and rare cases of hypercalcaemia with long-term high-dose treatment

Pregnancy & Lactation

  • Increased requirements for calcium and Vitamin D3 during pregnancy and lactation
  • Caution in administering calcium and iron supplements concurrently
  • Teratogenic effects of vitamin-D3 overdoses in pregnant animals
  • Potential teratogenic effects of long-term hypercalcaemia in humans
  • Presence of Vitamin-D3 and its metabolites in breast milk

Precautions & Warnings

  • Supervision for patients with mild to moderate renal failure or mild hypercalciuria
  • Periodic checks of plasma and urinary calcium levels
  • Measurement of urinary calcium excretion in patients with renal stones
  • Close monitoring of serum and urinary calcium levels and kidney function with long-term treatment
  • Calcium and Vitamin D3 supplementation allowances from other sources

Overdose Effects

  • Nausea
  • Vomiting
  • Severe drowsiness
  • Dry mouth
  • Loss of appetite
  • Metallic taste
  • Stomach cramps
  • Diarrhea
  • Headache
  • Constipation

Therapeutic Class

  • Specific mineral & vitamin combined preparations

Storage Conditions

  • Dry place away from light and heat
  • Keep out of the reach of children

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