G-Mag Sulph 4 gm/100 ml (IV Infusion)

100 ml vial: ৳ 50.00

Medicine Details

Category Details
Generic Magnesium sulfate
Company Gonoshasthaya pharma ltd
Also available as
G mag sulph 25 gm injection

Title

  • G-Mag Sulph

Categories

  • Medicine
  • Healthcare
  • Pharmacology

Description

G-Mag Sulph injection for the treatment of hypomagnesaemia, magnesium deficiency, irregular heart beats, laxative, anticonvulsant properties, prevention or control of seizures, bronchial asthma, cardiovascular disorder

Composition

  • Magnesium sulphate heptahydrate BP
  • 50% solution
  • 4% solution
  • Mg2+ approx. 2 mmol/ml
  • Mg2+ approx. 0.16 mmol/ml
  • Total 2.47gm
  • Total 4 gm

Pharmacology

Magnesium is essential for enzyme systems, energy generation, neurochemical transmission, muscular excitability, intracellular fluids

Indications

  • Hypomagnesaemia treatment
  • Irregular heart beats treatment
  • Laxative
  • Anticonvulsant properties
  • Seizure prevention
  • Bronchial asthma treatment
  • Cardiovascular disorder treatment

Dosage & Administration

  • Adult Dose:
    • Intramuscular 1-5g daily
    • Intravenous 1-4g
    • Electrolyte replenisher 1-2g 4 times a day
    • Usual dose range 1-40g daily
  • Pediatric Dose:
    • Intramuscular 20-40 mg/kg body weight
    • For Eclampsia 1-2g initially, 1g every 30 mins
  • Use in Children & Adolescents: Beneficial in moderate to severe asthma as adjuvant therapy

Mode of Action

Essential for enzyme systems, neurochemical transmission, muscular excitability, intracellular fluids

Interaction

  • With Medicine:
    • Reduction in blood pressure with Calcium channel blockers
    • Increase in effects of neuromuscular blocking agents
  • With Food & Others: No interaction with food & others

Contraindications

Defect of heart's electrical message pathways, severe damage to myocardium, significantly decreased kidney function

Side Effects

  • Common:
    • Hypermagnesaemia
    • Nausea
    • Vomiting
    • Flushing of skin
    • Thirst
    • Hypotension
    • Drowsiness
    • Confusion
    • Muscle weakness
  • Rare: Diarrhea, skin irritation after soaking

Pregnancy & Lactation

Crosses placenta, caution in pregnant women, unknown excretion in human milk

Precautions & Warnings

  • Administer with caution in impaired renal function or digitalis glycosides use
  • Monitor blood pressure, respiratory rate, urinary output, signs of overdose

Overdose Effects

Respiratory depression, loss of deep tendon reflexes, nausea, vomiting, hypotension, muscle weakness

Therapeutic Class

Specific mineral preparations

Storage Conditions

Store in a cool & dry place, keep away from light & children

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