Powersol 5% (IV Infusion)
500 ml bottle: ৳ 500.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amino acid d sorbitol electrolytes |
| Company | General pharmaceuticals ltd |
Indications
- Source of amino acids for protein synthesis
- Suitable for patients with basal amino acid requirements
- Faster recovery in surgery, burns, renal insufficiency, hepatic insufficiency
- Effective management of cancer
Composition
- Essential Amino Acids:
- L-Isoleucine 0.352 gm
- L-Leucine 0.490 gm
- L-Lysine Hydrochloride 0.430 gm
- L-Methionine 0.225 gm
- L-Phenylalanine 0.533 gm
- L-Threonine 0.250 gm
- L-Tryptophan 0.090 gm
- L-Valine 0.360 gm
- L-Histidine 0.250 gm
- L-Tyrosine 0.025 gm
- Non Essential Amino Acids:
- L-Arginine 0.500 gm
- L-Aspartic Acid 0.250 gm
- L-Glutamic Acid 0.075 gm
- L-Alanine 0.200 gm
- L-Cystine 0.010 gm
- Glycine (Aminoacetic Acid) 0.760 gm
- L-Proline 0.100 gm
- L-Serine 0.100 gm
- Excipients:
- D-Sorbitol 5.000 gm
- Electrolytes:
- Sodium (Na+) 57 mmol/L
- Potassium (K+) 25 mmol/L
- Magnesium (Mg++) 1.2 mmol/L
- Chloride (Cl-) 87 mmol/L
- Acetate (CH3COO-) 25 mmol/L
- Total Nitrogen Content: 7.25 gm/L
- Total Energy Content: 1551 kj/L (371.14 Kcal/L)
Pharmacology
- Sterile aqueous solution of crystalline Amino Acid and D-Sorbitol with electrolytes
- Contains all 18 essential and non-essential amino acids for protein synthesis
- Clear, colorless to pale yellow colored solution with pH 5.0 to 7.0
Dosage & Administration
- Dependent on patient's condition and metabolic stress
- Infusion range 0.10-0.25 g nitrogen/kg/day
- Slow infusion recommended for obese patients, children, and infants
Interaction
No pharmacological effects expected at recommended dosage
Contraindications
- Patients with inborn errors of amino acids metabolism
- Severe liver dysfunction
- Severe uremia when dialysis facilities are not available
- Patients with hyperosmolar nonketotic diabetic coma
Side Effects
- Rarely nausea, vomiting, flushing, sweating
- Transient increases in liver test
- Hypersensitivity reactions
- Thrombophlebitis with peripheral vein use
- Hyperphenylalaninemia in severely ill, premature infants
Pregnancy & Lactation
Successful and safe administration reported in humans, animal reproduction studies not carried out
Precautions & Warnings
- Increased urinary excretion of trace elements - copper and zinc
- Monitoring of phenylalanine level in severely ill, premature infants
- Caution in patients with diabetes mellitus, severe heart failure, and renal function issues
- Monitoring of serum potassium and blood glucose recommended
Overdose Effects
- Risk of nausea, vomiting, sweating, thrombophlebitis
- Osmotic diuresis with dehydration
- Symptoms related to hyperglycemia
Therapeutic Class
Parenteral nutritional preparations
Storage Conditions
Protect from light, store between 15°C to 25°C, avoid freezing, keep out of reach of children