Prosol 5% (IV Infusion)
500 ml bottle: ৳ 500.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amino acid d sorbitol electrolytes |
| Company | Incepta pharmaceuticals ltd |
Title
- Amino Acid IV Solution
Categories
- Medical Supplies
- Nutrition
- Intravenous Solutions
Description
- Indications: Source of amino acids for protein synthesis in patients needing intravenous nutrition, suitable for patients with basal amino acid requirements, faster recovery in surgery, burns, renal insufficiency, hepatic insufficiency, effective management of cancer
- Composition:
- EssentialAminoAcids:
- L-Isoleucine
- L-Leucine
- L-Lysine Hydrochloride
- L-Methionine
- L-Phenylalanine
- L-Threonine
- L-Tryptophan
- L-Valine
- L-Histidine
- L-Tyrosine
- NonEssentialAminoAcids:
- L-Arginine
- L-Aspartic Acid
- L-Glutamic Acid
- L-Alanine
- L-Cystine
- Glycine (Aminoacetic Acid)
- L-Proline
- L-Serine
- Excipients:
- D-Sorbitol
- Electrolytes:
- Sodium (Na+)
- Potassium (K+)
- Magnesium (Mg++)
- Chloride (Cl-)
- Acetate (CH3COO-)
- TotalNitrogenContent: 7.25 gm/L
- TotalEnergyContent: 1551 kj/L (371.14 Kcal/L)
- EssentialAminoAcids:
- Pharmacology: Sterile aqueous solution of crystalline Amino Acid and D-Sorbitol with electrolytes, necessary as the nitrogen source for parenteral nutrition, contains all 18 essential and non-essential amino acids needed for protein synthesis, clear, colorless to pale yellow colored, pH range of 5.0 to 7.0
- DosageAndAdministration:
- Adults:
- NoOrMinorMetabolicStressAndNormalNutritionalState: 0.10-0.15 g nitrogen/kg/day
- ModerateMetabolicStressWithOrWithoutMalnutrition: 0.15-0.20 g nitrogen/kg/day
- SevereCatabolismAsInBurnsSepsisAndTrauma: up to 0.20-0.25 g nitrogen/kg/day
- DosageRange: 0.10-0.25 g nitrogen/kg/day corresponds to 15-35 ml Amino acids IV/kg/day
- ObesePatients: dose based on estimated ideal weight, 1000-2000 ml Amino acids IV may be infused intravenously per 24 hours
- ChildrenAndInfants: Rate of infusion: 28-35 ml/kg body weight per day, with a step-wise increase in the rate of administration during the first week
- Adults:
- Interaction: No pharmacological effects expected, not expected to interact with other medicaments
- Contraindications: Inborn errors of amino acids metabolism, severe liver dysfunction, severe uremia when dialysis facilities are not available, contraindicated in patients with hyperosmolar nonketotic diabetic coma due to content of glucose
- SideEffects: Well-tolerated, rare occurrences of nausea, vomiting, flushing, sweating, transient increases in liver test, hypersensitivity reactions, thrombophlebitis, hyperphenylalaninemia in severely ill, premature infants
- PregnancyAndLactation: Successful and safe administration reported during pregnancy in humans, no animal reproduction studies conducted
- PrecautionsAndWarnings:
- UrinaryExcretion: Increased trace elements copper and zinc, which should be taken into account in dosing of trace elements, particularly during long-term IV nutrition
- Hyperphenylalaninemia: May occur in severely ill, premature infants, monitoring of phenylalanine level recommended, infusion rate to be adjusted as needed
- DiabetesAndHeartFailure: Use with caution, may require administration of exogenous insulin in patients with hyperglycemia, caution with refeeding carbohydrates in severely malnourished patients
- Hypophosphatemia: Additional supply of phosphate recommended
- Monitoring: Recommended for serum potassium and blood glucose if infused rapidly or in large quantity
- OverdoseEffects: Risk of nausea, vomiting, sweating, thrombophlebitis, osmotic diuresis with dehydration, symptoms related to hyperglycemia, slow down or discontinue infusion in case of overdose symptoms
- TherapeuticClass:
- Parenteral nutritional preparations
- StorageConditions:
- Protect from light
- Store between 15°C to 25°C
- Avoid freezing
- Keep out of reach of children