Repotyn 5% (IV Infusion)

500 ml bottle: ৳ 352.38

Medicine Details

Title and Category

  • Amino Acid IV Solution
  • Parenteral nutritional preparations

Dimensions

  • 100 ml solution (5%)

Color Options

  • Clear
  • Colorless
  • Pale yellow

Function

  • Source of amino acids for protein synthesis
  • Achieve positive nitrogen balance
  • Manage surgery recovery
  • Aid in burns recovery
  • Support renal insufficiency
  • Assist hepatic insufficiency
  • Manage cancer effectively

Materials

  • Essential and non-essential amino acids
  • D-Sorbitol
  • Electrolytes
  • Crystalline Amino Acid

Technical Specifications

  • Total Nitrogen Content: 7.25 gm/L
  • Total Energy Content: 1551 kj/L (371.14 Kcal/L)
  • pH range: 5.0 to 7.0
  • Electrolyte content: Sodium, Potassium, Magnesium, Chloride, Acetate

Composition

  • L-Isoleucine
  • L-Leucine
  • L-Lysine Hydrochloride
  • L-Methionine
  • L-Phenylalanine
  • L-Threonine
  • L-Tryptophan
  • L-Valine
  • L-Histidine
  • L-Tyrosine
  • L-Arginine
  • L-Aspartic Acid
  • L-Glutamic Acid
  • L-Alanine
  • L-Cystine
  • Glycine (Aminoacetic Acid)
  • L-Proline
  • L-Serine

Dosage & Administration

  • Dosage range: 0.10-0.25 g nitrogen/kg/day
  • Infusion rate: 1.4-2.8 ml (30-60 drops) per minute
  • Obese patient dosing based on estimated ideal weight
  • Children and infants: Infusion rate is 28-35 ml/kg body weight per day

Interaction

  • No pharmacological effects at recommended dosage

Contraindications

  • Inborn errors of amino acids metabolism
  • Severe liver dysfunction
  • Severe uremia without dialysis facilities
  • Hyperosmolar nonketotic diabetic coma (due to glucose content)

Side Effects

  • Rarely: Nausea
  • Observed during infusion: Vomiting, flushing, sweating
  • Transient increase in liver test during intravenous nutrition
  • Hypersensitivity reactions
  • Thrombophlebitis
  • Hyperphenylalaninemia in severely ill, premature infants

Pregnancy & Lactation

  • Reported successful and safe administration during pregnancy
  • No animal reproduction studies conducted

Precautions & Warnings

  • Increased urinary excretion of trace elements (copper, zinc)
  • Monitoring of phenylalanine level in severely ill, premature infants
  • Use with caution in patients with diabetes mellitus, severe heart failure, renal function, hyperglycemia, severe malnutrition, hypophosphatemia

Overdose Effects

  • Nausea
  • Vomiting
  • Sweating
  • Thrombophlebitis
  • Osmotic diuresis with dehydration
  • Symptoms related to hyperglycemia

Usability Features

  • Sterile aqueous solution
  • Necessary nitrogen source for parenteral nutrition
  • Suitable for patients with basal amino acid requirements

Pharmacology

  • Aids in achieving positive nitrogen balance
  • Contains all 18 essential and non-essential amino acids for protein synthesis

Therapeutic Class

  • Parenteral nutritional preparations

Storage Conditions

  • Protect from light
  • Temperature: 15°C to 25°C
  • Avoid freezing
  • Keep out of reach of children

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