Aminosin 5% (IV Infusion)
500 ml bottle: ৳ 350.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amino acid d sorbitol electrolytes |
| Company | Ibn sina pharmaceuticals ltd |
Indications
- Source of amino acids for protein synthesis
- Suitable for patients with basal amino acid requirements
- Faster recovery in surgery, burns, renal insufficiency, hepatic insufficiency, and cancer management
Composition
- EssentialAminoAcids:
- L-Isoleucine
- L-Leucine
- L-Lysine Hydrochloride
- L-Methionine
- L-Phenylalanine
- L-Threonine
- L-Tryptophan
- L-Valine
- L-Histidine
- L-Tyrosine
- NonEssentialAminoAcids:
- L-Arginine
- L-Aspartic Acid
- L-Glutamic Acid
- L-Alanine
- L-Cystine
- Glycine (Aminoacetic Acid)
- L-Proline
- L-Serine
- Excipients: D-Sorbitol
- Electrolytes:
- Sodium (Na+)
- Potassium (K+)
- Magnesium (Mg++)
- Chloride (Cl-)
- Acetate (CH3COO-)
- TotalNitrogenContent: 7.25 gm/L
- TotalEnergyContent: 1551 kj/L (371.14 Kcal/L)
Pharmacology
- Sterile aqueous solution of crystalline Amino Acid and D-Sorbitol with electrolytes
- Contains all 18 essential and non-essential amino acids for protein synthesis
- Clear, colorless to pale yellow colored
- pH range of 5.0 to 7.0
Dosage & Administration
- Adults:
- 0.10-0.25 g nitrogen/kg/day
- 15-35 ml Amino acids IV/kg/day
- ObesePatients: Dose based on estimated ideal weight
- Children&Infants: 28-35 ml/kg body weight per day
Interaction
No expected pharmacological effects or interactions with other medicaments
Contraindications
- Inborn errors of amino acids metabolism
- Severe liver dysfunction
- Severe uremia without dialysis facilities
- Hyperosmolar nonketotic diabetic coma
SideEffects
- Rarely nausea
- Vomiting and sweating at high infusion rates
- Transient increases in liver test
- Hypersensitivity reactions
- Thrombophlebitis risk
- Hyperphenylalaninemia in severely ill, premature infants
Pregnancy & Lactation
Reported successful and safe administration during pregnancy in humans
Precautions & Warnings
- IncreasedUrinaryExcretion: Trace elements copper and zinc
- HyperphenylalaninemiaMonitoring: Recommended for severely ill, premature infants
- CautionInUseWith:
- Diabetes mellitus
- Severe heart failure
- Renal function with fluid restrictions or oliguria/anuria
- Severely malnourished patients
- MonitoringRecommendation:
- Serum potassium
- Blood glucose
- AdditionalPhosphateSupply: Recommended for patients with hypophosphatemia
OverdoseEffects
- RiskOf:
- Nausea
- Vomiting
- Sweating
- Thrombophlebitis
- Osmotic diuresis
- Hyperglycemia symptoms
- Management: Slow down or discontinue infusion in case of overdose symptoms
TherapeuticClass
Parenteral nutritional preparations
StorageConditions
- Temperature: Between 15°C to 25°C
- Precaution: Protect from light and avoid freezing
- Safety: Keep out of reach of children