Fatisol 10% (IV Infusion)
Medicine Details
| Category | Details |
|---|---|
| Generic | Intravenous fat emulsion |
| Company | Popular pharmaceuticals ltd |
Title
Fatisol Intravenous Fat Emulsion
Categories
- Parenteral Nutritional Preparations
Description
Fatisol is a source of calories and essential fatty acids for patients requiring parenteral nutrition for extended periods of time. It is used in various indications including preoperative and postoperative nutritional disturbances, nutritional disorders due to inadequate intestinal absorption, burns, impaired renal function, cachexia, and essential fatty acid deficiency. The composition includes refined soyabean oil, purified egg lecithin, and glycerol. It is administered intravenously, and the dosage varies for adults, children, and infants. It should be used with caution during pregnancy and lactation. Precautions include monitoring in neonates and premature infants, and it should be stored at 15°C to 30°C in a dry place protected from light.
Indications
- Source of calories and essential fatty acids
- Improves nitrogen balance
- Treats nutritional disorders
- Reduces excessive nitrogen losses
- Used in prolonged unconsciousness
- Indicated for impaired renal function
- Treats cachexia
- Corrects essential fatty acid deficiency
Composition
- Refined Soyabean Oil (10 gm per 100 ml)
- Purified Egg Lecithin (1.2 gm per 100 ml)
- Glycerol (2.25 gm per 100 ml)
Pharmacology
- Prevents Essential Fatty Acid Deficiency
- Provides mixture of neutral triglycerides
- Contains linoleic, oleic, palmitic acids
- Contains egg yolk phospholipids as an emulsifier
- Formulated as a concentrated source of energy
- Provides basal phosphate and vitamin E
Dosage
- Administer as part of Total Parenteral Nutrition (TPN)
- Dosage varies for adults, children, and infants
- For correcting Essential Fatty Acid Deficiency
Administration
- Given via peripheral or central vein
- May be given simultaneously with amino acids and/or glucose
Interaction
- Possible interaction with insulin and heparin
Contraindications
- Severely disordered fat metabolism
- Severe liver damage
- Acute shock
- Hypersensitivity to egg-, soya- or peanut protein
Side Effects
- Rise in body temperature
- Shivering
- Nausea/vomiting
- Hypersensitivity reactions
- Respiratory symptoms
- Circulatory effects
- Thrombosis
- Neurological adverse reactions
Pregnancy & Lactation
- Administer with caution during pregnancy and lactation
Precautions & Warnings
- May cause allergic reactions
- Cross allergic reaction observed between soya-bean and peanut
- Should be administered with caution in certain conditions
- Monitor in neonates and premature infants
Overdose Effects
- May lead to fat overload syndrome
- Characterized by bone marrow depression, hepatosplenomegaly, fever, and shock
- Symptoms reversible if infusion is discontinued
Therapeutic Class
- Parenteral Nutritional Preparations
Storage Conditions
- Store at 15°C to 30°C in a dry place protected from light
- Do not use if evidence of excessive creaming or aggregation
- Discard leftover contents of opened bag or bottles
- Contains no preservatives