Clovir 400 mg (Tablet)

Unit Price: ৳ 22.00 (2 x 10: ৳ 440.00)
Strip Price: ৳ 220.00

Medicine Details

Category Details
Generic Acyclovir oral
Company Ibn sina pharmaceuticals ltd
Also available as

Title

  • Aciclovir

Categories

  • Antiviral Medication
  • Herpes Treatment
  • Infection Prevention
  • Immunocompromised Care

Description

  • Synthetic purine derivative
  • Interferes with DNA synthesis
  • Inhibits viral replication

Dimensions

  • N/A

Color options

  • N/A

Functions

  • Treats viral infections due to Herpes simplex virus and Varicella zoster virus
  • Prophylaxis of Herpes simplex infections in immunocompromised patients
  • Reduces toxicity risk
  • Contradiction in hypersensitivity

Materials

  • N/A

Technical specifications

  • 15-30% oral absorption from GI tract
  • Peak plasma concentrations within 1.5-2 hours
  • Widely distributed in body tissues and fluids
  • Excreted through kidney by glomerular filtration & tubular secretion

Design elements

  • Pregnancy category B
  • Caution in renal impairment cases
  • Therapeutic class for Herpes simplex & Varicella-zoster virus infections

Usability features

  • Dosage adjusted according to renal impairment
  • Monitoring of neutrophil count in neonates

Interaction

  • Probenecid reduces Aciclovir excretion

Contraindications

  • Hypersensitivity to Aciclovir

Side effects

  • Rash
  • Gastrointestinal disturbance
  • Rise in bilirubin and liver-related enzymes
  • Increase in blood urea and creatinine
  • Decrease in hematological indices
  • Headache
  • Neurological reaction
  • Fatigue

Pregnancy and lactation

  • Caution in pregnancy and lactation, unless potential benefit justifies risk to fetus
  • Caution in breastfeeding

Precautions and warnings

  • Caution in renal impairment cases
  • Dose adjustment according to creatinine clearance
  • Neutrophil count monitoring in neonates

Storage conditions

  • Store below 25°C
  • Protected from light and moisture
  • Keep out of reach of children

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