Neorice (Oral Powder)

Indications

• Acute fluid and electrolyte loss conditions such as cholera, acute diarrhea & vomiting
• Dehydration
• Severely low concentrations of salts in the blood (severe electrolyte depletion)

Composition

• For 500 ml water:
  • Sodium Chloride BP 1.3 gm
  • Potassium Chloride BP 0.75 gm
  • Tri-sodium Citrate Dihydrate BP 1.45 gm
  • Processed Rice Powder Pharma Grade 25 gm
• For 250 ml water:
  • Sodium Chloride BP 0.65 gm
  • Potassium Chloride BP 0.375 gm
  • Tri-sodium Citrate Dihydrate BP 0.725 gm
  • Processed Rice Powder Pharma Grade 12.5 gm

Pharmacology

• Contains essential electrolytes & carbohydrate
• Facilitates the absorption of sodium
• Needed to replace body losses of essential ions
• Corrects the acidosis
• Rice reduces the osmolarity of the solution

Dosage & Administration

• Dependent on severity of dehydrating conditions
• Recommended dose after each watery stool:
  • 6 months to 2 years: 50-100 ml
  • 2 years to 9 years: 100-200 ml
  • 10 years and above: 250-500 ml
• Reconstitution Procedure for 250 ml saline:
  • Add 250 ml hot boiled water into a jar
  • Mix the powder well in the water until a milky white solution appears
  • Discard any unused reconstituted saline after 5 hours
• Reconstitution Procedure for 500 ml saline:
  • Add 500 ml hot boiled water into a jar
  • Mix the powder well in the water until a milky white solution appears
  • Discard any unused reconstituted saline after 5 hours
• Do not further heat or boil the solution
• Use a clean spoon each time before administration
• Syringe without needle may be used for infants

Interaction

• No known drug interactions reported

Contraindications

• Kidney failure resulting in diminished production of urine (oliguria)
• Kidney failure preventing the production of urine (anuria)
• Obstruction of the stomach or intestines
• Reduced blood flow to vital internal organs (shock)
• Severe and continuous vomiting (intractable vomiting)
• Severe dehydration
• Severe diarrhea in infants

Pregnancy & Lactation

• Recommended in pregnancy & lactation, no known harmful effects

Precautions & Warnings

• Precautions for significant overdose
• Especially for children less than 1 year of age
• Patients with electrolyte imbalance
• Patients with severely decreased kidney and liver function

Therapeutic Class

• Oral electrolytes preparations

Storage Conditions

• Store in a cool & dry place, protected from light & moisture

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