Dextran 40 10%+0.9% (IV Infusion)

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Medicine Details

Indications

  • Aid in Hysteroscopy
  • Thromboembolic disorders
  • Prophylaxis of pulmonary embolism or venous thrombosis
  • Hypovolaemic shock

Pharmacology

  • Expands plasma volume
  • Reduces blood viscosity
  • Inhibits sludging or aggregation of red blood cells
  • Restores sodium ions

Dosage & Administration

  • Intrauterine aid in hysteroscopy
  • Intravenous thromboembolic disorders
  • Prophylaxis of pulmonary embolism or venous thrombosis
  • Prophylaxis of postoperative thromboembolic disorders
  • Intravenous hypovolaemic shock

Interaction

  • Enzyme inducers
  • Enzyme inhibitors
  • May affect serum concentrations of lithium

Contraindications

  • Hypersensitivity
  • Severe renal disease with oliguria or anuria
  • Marked cardiac decompensation
  • Pregnancy

Side Effects

  • GI disturbances
  • Headache
  • Dizziness
  • Allergic reactions
  • Raised liver enzyme values
  • Alopecia
  • Bone marrow suppression

Pregnancy & Lactation

  • Category C - potential benefit justifies potential risk to the fetus

Precautions & Warnings

  • Lactation

Therapeutic Class

  • Plasma expanders

Storage Conditions

  • Store at 25°C

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