Calcitonin 100 IU/ml (Injection)

1 ml ampoule: ৳ 145.00 (2 x 5: ৳ 1,450.00)

Medicine Details

Category Details
Generic Salmon calcitonin
Company City overseas ltd

Indications

  • Active Paget's disease
  • Hypercalcaemia
  • Non-responsive patients
  • Alternative treatments

Composition

  • Salmon Calcitonin
  • Polyacetate polyhydrate
  • Sodium acetate
  • Glacial acetic acid
  • Sodium chloride
  • Amino-acid sequence
  • Molecular weight
  • Solubility

Description

  • Synthesis by parafollicular cells
  • Potency standardisation
  • Plasma calcium level reduction

Pharmacology

  • Polypeptide hormone
  • Osteoclastic bone resorption inhibition
  • Bone turnover reduction
  • Renal excretion promotion

Dosage & Administration

  • Intravenous administration
  • Emergency treatment of hypercalcaemia
  • Parenteral administration
  • Adjunct in hypercalcaemia
  • Adjunct in Paget's disease of bone
  • Nasal administration
  • Postmenopausal osteoporosis

Interaction

  • Concurrent use with cardiac glycosides
  • Dosage adjustments
  • Lithium concentration decrease

Contraindications

  • Hypersensitivity
  • Hypocalcaemia patients

Side Effects

  • GI disturbances
  • Dizziness
  • Flushing
  • Tingling of the hands
  • Unpleasant taste
  • Skin rash
  • Abdominal pain
  • Urinary frequency
  • Tremor
  • Injection site inflammation
  • Diabetogenic effect

Pregnancy & Lactation

  • Pregnancy Category C
  • Adverse effects on the fetus
  • Potential benefit justifies potential risk

Precautions & Warnings

  • Skin test before therapy
  • Heart failure
  • Renal impairment
  • Pregnancy
  • Lactation
  • Children

Use in Special Populations

  • Renal Impairment
  • Dosage adjustment needed

Overdose Effects

  • Flushing
  • Nausea
  • Vomiting
  • Dizziness
  • Symptomatic treatment
  • Supportive treatment

Therapeutic Class

  • Hormone in bone formation
  • Inhibiting bone resorption

Storage Conditions

  • Temperature range 2-8°C

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