Articulex 250 mg+200 mg (Tablet)

Indications

• Treatment of osteoarthritis of knee, hip, spine, hand and other locations
• Beneficial in rheumatoid arthritis
• Beneficial in sports injuries
• Beneficial for migraine
• Beneficial for skin problems like psoriasis
• Beneficial for vascular complications like atherosclerosis
• Beneficial for kidney stones
• Beneficial for inflammatory bowel disease

Pharmacology

• Glucosamine is a natural amino-sugar
• Building block for biosynthesis of glycosaminoglycans (GAGs)
• Formation of proteoglycans
• Helps to form ligaments, tendon, nails and connective tissues
• Increases Glucosamine level in the body
• Activates chondrocytes in the cartilage
• Chondroitin Sulfate is a glycosaminoglycan found in connective tissue
• Protects existing healthy cartilage from premature decline
• Synergistic effect with Glucosamine Sulfate

Dosage and administration

• 250/200 mg tablet
• 1 to 2 tablets, three times daily
• Dose may be adjusted according to the response and body weight
• Doses can be tapered after 60 days
• Typical dosage recommendation based on body weight
• 750/600 mg tablet
• 1 tablet two times daily or as directed by the physician

Interaction

• No significant drug interactions reported
• Chondroitin may enhance the blood thinning effects of anticoagulants like Warfarin, Heparin

Contraindications

• No known contraindications
• Proven hypersensitivity to Glucosamine and Chondroitin is a contraindication

Side effects

• Safety studies show no demonstrable side effects
• Rarely occurring side effects are almost like placebo
• Mild and reversible intestinal flatulence

Pregnancy and lactation

• Not recommended for pregnant or potentially pregnant women
• Effects on developing fetus not studied enough
• No studies on use during pregnancy or lactation
• Should be taken with caution and medical advice during pregnancy and lactation

Precautions and warnings

• Diabetic patients advised to monitor blood glucose levels regularly
• No special studies in patients with renal or hepatic insufficiency
• Administration to patients with severe hepatic or renal insufficiency should be under medical supervision
• Children should not be supplemented

Therapeutic class

• Stimulation of Cartilage formation

Storage conditions

• Store in a cool and dry place, protected from light

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