Joinix Plus 250 mg+200 mg (Tablet)

Indications

• Treatment of osteoarthritis of knee, hip, spine, hand, and other locations
• Beneficial in rheumatoid arthritis
• Beneficial in sport injuries
• Beneficial in migraine
• Beneficial in skin problems (e.g., psoriasis)
• Beneficial in vascular complications (e.g., atherosclerosis)
• Beneficial in kidney stones
• Beneficial in inflammatory bowel disease (e.g., ulcerative colitis, leaky gut syndrome)

Pharmacology

• Glucosamine is a natural amino-sugar
• Fundamental building block for biosynthesis of glycosaminoglycans (GAGs)
• Found in certain foods
• Building block of articular cartilage
• Helps form ligaments, tendon, nails, and connective tissues
• Increases Glucosamine level in the body
• Activates chondrocytes in the cartilage
• Chondroitin Sulfate is a glycosaminoglycan found in connective tissue
• Protects healthy cartilage from premature decline
• Combining Glucosamine with Chondroitin Sulfate shows synergistic effect

Dosage & Administration

• 250/200 mg tablet: 1 to 2 tablets, three times daily
• Dose may be adjusted according to the response of the drug and body weight
• Doses can be tapered after 60 days as per requirement
• 750/600 mg tablet: 1 tablet two times daily or as directed by the physician
• Dosage recommendations based on body weight

Interaction

• No significant drug interactions reported with specific medications
• Chondroitin may enhance the blood thinning effects of anticoagulants like Warfarin, Heparin

Contraindications

• No known contraindications for Glucosamine and Chondroitin
• Proven hypersensitivity (e.g. allergic to shellfish or sulfur) is a contraindication

Side Effects

• Safety studies show no demonstrable side effects
• Rarely occurring side effects are almost like placebo
• Mild & reversible intestinal flatulence

Pregnancy & Lactation

• Not recommended for pregnant women or those who could become pregnant
• Insufficient studies on effects during pregnancy and lactation
• Should be taken with caution and medical advice during pregnancy and lactation

Precautions & Warnings

• Patients with Diabetes Mellitus are advised to monitor blood glucose levels regularly when taking Glucosamine
• No special studies in patients with renal or hepatic insufficiency
• No limitations indicated for patients with severe hepatic or renal insufficiency
• Children should not be supplemented with Glucosamine and Chondroitin

Therapeutic Class

• Stimulation of Cartilage formation

Storage Conditions

• Store in a cool and dry place, protected from light

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