Cyclomide 200 mg/vial (IV Infusion)
200 mg vial: ৳ 150.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cyclophosphamide |
| Company | Techno drugs ltd |
| Also available as |
Indications
- Malignant lymphomas treatment
- Hodgkin’s disease treatment
- Leukemias treatment
- Multiple myeloma treatment
- Neuroblastoma treatment
- Adenocarcinoma of the ovary treatment
- Retinoblastoma treatment
- Carcinoma of the breast treatment
- Nonmalignant disease treatment - Minimal Change Nephrotic Syndrome in Children
Pharmacology
- Liver biotransformation
- Alkylating metabolites
- Growth interference of malignant cells
- DNA cross-linking mechanism of action
- Oral absorption bioavailability
- Elimination half-life
- Plasma protein binding
- Renal excretion
- Cytotoxic and noncytotoxic metabolites
- Plasma concentration peaks
Dosage & Administration
- Intravenous initial course
- Intravenous regimens
- Oral dosing range
- Adjustable dosages based on antitumor activity
- Leukocyte count regulation
- Combined cytotoxic regimen adjustments
- Dialyzable properties
- Renal function impact on pharmacokinetics
- Nonmalignant disease dosing
Interaction
- Metabolism rate
- Leukopenic activity
- Phenobarbital interaction
- Chronic administration effects
- Concurrent drug actions
- Cholinesterase inhibition effects
- Anesthesia interaction
Contraindications
- Severely depressed bone marrow function
- Hypersensitivity
Side Effects
- Nausea and vomiting
- Anorexia
- Abdominal discomfort
- Hemorrhagic colitis
- Alopecia
- Skin rash
- Leukopenia
- Thrombocytopenia
- Hemorrhagic ureteritis
- Interstitial pneumonitis
- Anaphylactic reactions
- Syndrome of inappropriate ADH secretion
Pregnancy & Lactation
- Pregnancy Category D
- Excretion in breast milk
- Tumorigenicity potential
- Nursing decision
Precautions & Warnings
- Toxicity development conditions
- Leukopenia
- Thrombocytopenia
- Tumor cell infiltration
- X-ray therapy history
- Cytotoxic agent therapy history
- Impaired hepatic function impact
- Impaired renal function impact
Use in Special Populations
- Pediatric use safety profile
- Geriatric use data insufficiency
Overdose Effects
- Supportive measures management
- Concurrent infection treatment
- Myelosuppression treatment
- Cardiac toxicity treatment
Therapeutic Class
- Cytotoxic Chemotherapy
Storage Conditions
- Temperature restrictions
- Protection from light and moisture
- Freezing avoidance