Adorex 5 mg/5 ml (Oral Suspension)

60 ml bottle: ৳ 28.10

Medicine Details

Category Details
Generic Domperidone maleate
Company Ambee pharmaceuticals ltd
Also available as
Adorex 10 mg tablet Adorex 5 mg pediatric drop

Title

  • Adorex 5 mg/5 ml Suspension

Category

  • Medicine
  • Gastrointestinal

Indications

  • Dyspeptic symptom complex
  • Acute nausea and vomiting
  • Parkinson's disease
  • Radiological studies

Pharmacology

  • Dopamine antagonist
  • ChemoreceptorTrigger Zone (CTZ) blocker
  • Gastroprokinetic action
  • Enhances antral and duodenal peristalsis

Dosage/Administration

  • Should be taken 15-30 minutes before meals
  • Adult dose: 10-20 mg (1-2 tablets) every 6-8 hours daily
  • Maximum dose: 80 mg daily

Interaction

  • Antagonized by anticholinergic drugs
  • Simultaneous use with antacids and antisecretory drugs to be avoided
  • Metabolized by CYP3A4
  • Potential impact on concomitantly orally administered drugs

Contraindications

  • Known hypersensitivity
  • Neonates
  • Gastrointestinal hemorrhage, mechanical obstruction or perforation
  • Prolactin releasing pituitary tumor (prolactinoma)

Side Effects

  • Transient intestinal cramps
  • Rare extrapyramidal phenomena
  • Increase in plasma prolactin level
  • Allergic reactions like rash and urticaria

Pregnancy & Lactation

  • Not recommended during the first trimester of pregnancy
  • Excreted in breast milk
  • Concentrations in breast milk are 4 times lower than plasma concentrations

Precautions & Warnings

  • Caution in children due to risk of extra-pyramidal reactions
  • Caution in patients with hepatic impairment

Use in Special Populations

  • Caution in infants and patients with liver or kidney disorders

Overdose Effects

  • Symptoms may include drowsiness, disorientation and extrapyramidal reactions
  • Activated charcoal administration recommended

Therapeutic Class

  • Motility Stimulants
  • Dopamine antagonist
  • Prokinetic drugs

Storage Conditions

  • Store below 30°C
  • Protected from light & moisture
  • Keep out of children's reach

Chemical Structure

  • Molecular Formula: C22H24ClN5O2

FAQs

  • Used to treat nausea and vomiting
  • Adverse effects include dizziness, sleepiness, dry mouth, watery diarrhea

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