Gemzar 200 mg/vial (IV Infusion)

200 mg vial: ৳ 2,300.00

Medicine Details

Category	Details
Generic	Gemcitabine
Company	Eli lilly and company
Also available as	Gemzar 1 gm injection Gembine 200 mg injection Gembine 1 gm injection

Title and Categories

Gemzar
Cytotoxic Chemotherapy

Indications

Non-Small Cell Lung Cancer
Pancreatic Cancer
Bladder Cancer
Breast Cancer
Ovarian Cancer

Dosage and Administration

Single-agent Use
Combination Use
Recommended Dose
Intravenous Infusion
Cycle Duration
Dosage Reduction
Metastatic Adenocarcinoma
Refractory Pancreatic Cancer

Pharmacology

Metabolism
Active Nucleoside
Cytotoxic Action
Inhibition of DNA Synthesis
Inhibition of Ribonucleotide Reductase

Interaction

No confirmed interactions reported
No specific drug interaction studies conducted

Contraindications

Known Hypersensitivity to Gemcitabine
Hypersensitivity to any other components of this product

Side Effects

Haematological Toxicity
Leukopenia
Thrombocytopenia
Hepatic Toxicity
Gastrointestinal Effects
Genito-Urinary Toxicity
Pulmonary Toxicity
Allergic Toxicity
Neurotoxicity
Alopecia

Pregnancy & Lactation

Pregnancy Category D
Use during pregnancy, excretion in human breast milk unknown

Precautions & Warnings

Schedule-dependent Toxicity
Myelosuppression
Pulmonary Toxicity and Respiratory Failure
Hemolytic Uremic Syndrome
Hepatic Toxicity
Embryofetal Toxicity
Radiation Therapy Toxicity
Impairment of Fertility

Use in Special Populations

Elderly Patients
Renal and Hepatic Impairment
Children

Overdose Effects

No known antidote for overdoses
Myelosuppression
Paresthesias
Severe Rash
Supportive Therapy

Storage Conditions

Store in original carton
Temperature Range 20°C to 25°C
Protection from light
Avoid refrigeration

Mode of Action

Inhibition of RNA
Induction of Apoptosis
DNA Polymerase Inhibition
Self-potentiation
Cellular Death Process

Pediatric Uses

Limited Phase I and II Trials
Efficacy and Safety

Drug Classes

Cytotoxic Chemotherapy

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