Anet 10 mg (Tablet)

Unit Price: ৳ 2.00 (100's pack: ৳ 200.00)

Medicine Details

Category Details
Generic Domperidone maleate
Company Kemiko pharmaceuticals ltd
Also available as
Anet 5 mg suspension

Title

Anet 10 mg Tablet

Categories

  • Medicine
  • Gastrointestinal
  • Antiemetic
  • Dopamine Antagonist
  • Prokinetic Agent

Description

Anet 10 mg Tablet is a medication used to treat dyspeptic symptom complex, acute nausea and vomiting, Parkinson's disease, and speeding barium transit in radiological studies. It is a dopamine antagonist that promotes gastric motility and provides relief from gastrointestinal symptoms.

Color options

  • White

Dosage form

Tablet

Packaging

Blister pack, Bottle

Strength

10 mg

Manufacturer

Manufacturer Name

Active ingredient

Domperidone

Chemical structure

C22H24ClN5O2

Pharmacology

  • Blocks dopamine receptors in Chemoreceptor Trigger Zone and stomach
  • Restores normal motility and tone of the upper gastrointestinal tract
  • Facilitates gastric emptying and enhances peristalsis

Indication

  • Dyspeptic symptom complex
  • Acute nausea and vomiting
  • Parkinson's disease
  • Radiological studies

Recommended dosage

  • Adults: 10-20 mg every 6-8 hours daily (maximum dose of 80 mg daily)
  • Children: 2-4 ml suspension/10 kg body weight every 6-8 hours daily

Route of administration

  • Oral
  • Rectal

Interaction

  • Antagonistic drugs: Anticholinergics
  • Inhibitors: CYP3A4 inhibitors (e.g., azole antifungals, macrolide antibiotics, HIV protease inhibitors)

Contraindications

  • Hypersensitivity to domperidone
  • Neonates
  • Gastrointestinal hemorrhage, obstruction or perforation
  • Prolactin releasing pituitary tumor

Side effects

  • Common:
    • Transient intestinal cramps
  • Rare:
    • Extrapyramidal phenomena
    • Hyperprolactinaemia
    • Allergic reactions such as rash and urticaria

Pregnancy lactation

Use during the first trimester of pregnancy justified by therapeutic benefit. Caution advised during lactation.

Precautions warnings

  • Caution in children due to risk of extra-pyramidal reactions
  • Use with caution in patients with hepatic impairment

Special populations

  • Infants: Caution advised due to incompletely developed blood-brain barrier
  • Liver disorders: Caution advised due to high metabolism in the liver
  • Kidney disorders: Dosage adjustment may be necessary in severe renal insufficiency

Overdose effects

  • Drowsiness
  • Disorientation
  • Extrapyramidal reactions

Therapeutic class

Motility Stimulant/Dopamine Antagonist

Storage conditions

Store below 30°C, protected from light & moisture

Storage precautions

Keep out of children's reach

Additional information

  • Domperidone does not affect mental alertness

Additional guidelines

  • Take 15-30 minutes before meals
  • Avoid concomitant use with antacids and antisecretory drugs

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