Campto 20 mg/ml (IV Infusion)
100 mg vial: ৳ 11,957.63
Medicine Details
| Category | Details |
|---|---|
| Generic | Irinotecan hydrochloride |
| Company | Pfizer |
Indications
- Metastatic carcinoma of the colon or rectum
- First-line therapy
- Fluorouracil-based therapy
- Recurred or progressed disease
Pharmacology
- Derivative of Camptothecin
- Interaction with topoisomerase I
- Reversible single-strand breaks
- Binding to topoisomerase I-DNA complex
Dosage & Administration
- Colorectal cancer combination regimen 1
- Colorectal cancer combination regimen 2
- Colorectal cancer single agent regimen 1
- Colorectal cancer single agent regimen 2
Interaction
- Risk with diuretics
- Enhancement by prophylactic dexamethasone
- Increased incidence with prochlorperazine
- Reduction by St John's wort, ketoconazole
Contraindications
- Known hypersensitivity to the drug or its excipients
Side Effects
- Nausea
- Vomiting
- Abdominal pain
- Diarrhea
- Constipation
- Anorexia
- Mucositis
- Neutropenia
- Leukopenia
- Anemia
- Thrombocytopenia
- Asthenia
- Pain
- Fever
- Infection
- Abnormal bilirubin
- Alopecia
Pregnancy & Lactation
- Pregnancy category D
- Fetal harm
- Excretion in human milk
Precautions & Warnings
- Diarrhea and Cholinergic Reactions
- Myelosuppression
- Patients with Reduced UGT1A1 Activity
Use in Special Populations
- Pediatric Use
- Geriatric Use
- Renal Impairment
- Hepatic Impairment
Therapeutic Class
- Cytotoxic Chemotherapy
Storage Conditions
- Controlled room temperature 15° to 30°C
- Protection from light
- Storage in carton until use