Eloxatin 5 mg/ml (IV Infusion)
50 mg vial: ৳ 8,215.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Oxaliplatin |
| Company | Synovia pharma plc |
Title and Categories
- Eloxatin
- Cytotoxic Chemotherapy
Indications
- Adjuvant treatment of stage III colon cancer
- Treatment of advanced colorectal cancer
Pharmacology
- Formation of transient reactive species
- Formation of DNA crosslinks
- Cytotoxicity
- Antitumor activity against colon carcinoma
Dosage & Administration
- Administered in combination with 5-fluorouracil/folinic acid
- Recommended treatment duration
- Specific administration protocol on Day 1 and Day 2
Interactions
- No specific cytochrome P-450-based drug interaction studies conducted
- Potential interaction with nephrotoxic compounds
Contraindications
- Known allergy to oxaliplatin or other platinum compounds
Side Effects
- Peripheral sensory neuropathy
- Neutropenia
- Thrombocytopenia
- Nausea
- Increase in transaminases and alkaline phosphatase
- Diarrhea
- Emesis
- Fatigue
- Stomatitis
- Other reported adverse reactions
Pregnancy & Lactation
- Pregnancy Category D
- Potential fetal harm
- Advice for women of childbearing potential
- Unknown excretion in human milk
Precautions & Warnings
- Observation of allergic reactions
- Monitoring for neurological toxicity
- Monitoring for pulmonary toxicity
- Investigation of hepatotoxicity
- Monitoring for cardiovascular toxicity
Overdose Effects
- No known antidote
- Anticipated complications of overdose
- Observed adverse reactions from reported cases
- Monitoring and supportive treatment
Storage Conditions
- Cool and dry storage
- Protection from light and moisture
- Keep out of reach of children