Xaloplat 5 mg/ml (IV Infusion)
50 mg vial: ৳ 3,000.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Oxaliplatin |
| Company | Beacon pharmaceuticals plc |
Indications
- Adjuvant treatment of stage III colon cancer
- Treatment of advanced colorectal cancer
Pharmacology
- Formation of reactive species
- Inhibition of DNA replication and transcription
- Cell-cycle nonspecific cytotoxicity
Dosage & Administration
- Recommended dosage schedule
- Recommended administration method
- Duration of treatment
Interaction
- Absence of specific cytochrome P-450-based drug interactions
- Potential effect on plasma concentrations of 5-fluorouracil
- Potential decrease in clearance with nephrotoxic compounds
Contraindications
- Known allergy to oxaliplatin or other platinum compounds
Side Effects
- Common adverse reactions
- Incidence of common adverse reactions
- Reported serious adverse reactions
Pregnancy & Lactation
- Pregnancy Category D
- Potential fetal harm
- Recommendations for women of childbearing potential
- Potential excretion in human milk
Precautions & Warnings
- Management of allergic reactions
- Monitoring neurological toxicity
- Preventing acute laryngopharyngeal dysaesthesias
- Management of pulmonary toxicity
- Investigation of hepatotoxicity
- Monitoring cardiovascular toxicity
Overdose Effects
- Absence of known antidote
- Anticipated complications of overdose
- Reported adverse reactions in overdose cases
- Maximum administered dose in a single infusion
Therapeutic Class
- Cytotoxic Chemotherapy
Storage Conditions
- Recommendations for storage
- Protection from light and moisture
- Safety precautions for children