Trastunix 440 mg/20 ml (IV Infusion)
440 mg vial: ৳ 80,000.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Trastuzumab |
| Company | Beacon pharmaceuticals plc |
Indications
- Adjuvant Breast Cancer
- Metastatic Breast Cancer
- Metastatic Gastric Cancer
Mode of Action
- Inhibition of HER2 overexpression
- Antibody-dependent cellular cytotoxicity
Dosage
- Administer as intravenous infusion
- Initial dose based on treatment regimen
- Subsequent doses based on cancer type and treatment stage
Administration
- Reconstitution with diluent
- Storage in refrigerator
- Visual inspection for particulate matter and discoloration
Interaction
- Increased risk of cardiac dysfunction with anthracycline use
- Monitoring of cardiac function post-treatment
Side Effects
- Cardiomyopathy
- Infusion Reactions
- Embryo-Fetal Toxicity
- Pulmonary Toxicity
- Exacerbation of Chemotherapy-Induced Neutropenia
Pregnancy & Lactation
- Fetal harm warning
- Necessity of effective contraception during treatment
Precautions & Warnings
- Cardiac Monitoring
- Infusion Reactions management
- Embryo-Fetal Toxicity caution
- Pulmonary Toxicity risk
- Neutropenia exacerbation
Use in Special Populations
- No established safety and effectiveness in pediatric patients
Reconstitution
- Use of Bacteriostatic Water for Injection
- Alternative for patients with benzyl alcohol hypersensitivity
Storage Conditions
- Refrigeration at 2°C to 8°C
- Protection from light
- Discard unused product after 28 days
- No freezing