Myfortic 180 mg (Tablet (Delayed Release))
Unit Price: ৳ 75.00 (12 x 10: ৳ 9,000.00)
Strip Price: ৳ 750.00
Medicine Details
Category | Details |
---|---|
Generic | Mycophenolic acid |
Company | Novartis bangladesh ltd |
Also available as |
Indications
- Prophylaxis of organ rejection in kidney transplant in adult patients
- Prophylaxis of organ rejection in pediatric patients 5 years of age and older
Pharmacology
- Mycophenolic acid delayed-release tablets are enteric coated formulation of mycophenolate sodium
- Immunosuppressive agent
- Inhibitor of inosine monophosphate dehydrogenase (IMPDH)
- Prevent acute rejection of kidney and heart allotransplantation
- Decreases antibody production
- Cytostatic effects on lymphocytes
Dosage & Administration
- Recommended dose of Mycophenolic acid is 720 mg administered twice daily (1440 mg total daily dose) for adult kidney transplant patients
- Recommended dose of Mycophenolic acid in conversion (at least 6 months post-transplant) pediatric patients age 5 years and older is 400 mg/m2 body surface area (BSA) administered twice daily
- Tablets should be taken on an empty stomach, 1 hour before or 2 hours after food intake
- Tablets should not be crushed, chewed, or cut prior to ingesting
Interaction
- Caution should be exercised with concomitant administration of Antacids, Azathioprine, Cyclosporin, Rifampin, Sevelamer, Cholestyramine, Acyclovir, Metronidazole, Hormonal contraceptives as these medicines may decrease Myfortic concentration
Contraindications
- Mycophenolic acid delayed-release tablets and Mycophenolate mofetil tablets and capsules should not be used interchangeably without physician supervision because the rate of absorption following the administration of these two products is not equivalent
Side Effects
- Anemia
- Leukopenia
- Constipation
- Diarrhea
- Vomiting
- Dyspepsia
- Urinary tract infection
- CMV infection
- Insomnia
- Postoperative pain
Pregnancy & Lactation
- Pregnancy Category D. Can cause fetal harm
- Discontinue Mycophenolic acid or discontinue nursing while on treatment or within 6 weeks after stopping therapy. Take into consideration the importance of the drug to the mother
Precautions & Warnings
- Can cause embryofetal toxicity
- Can increase new or reactive viral infections
- Can cause blood dyscrasias including pure red cell aplasia
- Can cause serious GI tract complications (gastrointestinal bleeding, perforations and ulcers)
- May increase the risk of developing lymphomas and other malignancies, particularly of the skin
- Use of live vaccine should be avoided during treatment with Myfortic
Overdose Effects
- No data available with regard to overdose
Therapeutic Class
- Immunosuppressant
Storage Conditions
- Store at 25°C and Keep out of reach of children