Simplovir 200 mg (Tablet)
Unit Price: ৳ 14.00 (3 x 10: ৳ 420.00)
Strip Price: ৳ 140.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Acyclovir oral |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Title and Categories
- Aciclovir
- Anti-viral Medication
- Herpes Treatment
- Varicella-zoster Treatment
Dosage and Administration
- Recommended dosage for initial herpes simplex
- Dosage for immunocompromised patients
- Prevention of recurrence of herpes simplex
- Prophylactic treatment of herpes simplex in immunocompromised patients
- Treatment of varicella (chicken pox)
- Treatment of herpes zoster (shingles)
- Treatment of initial rectal (proctitis) herpes infections
- Dosage adjustment for patients with severe renal impairment
Indications
- Treatment of viral infections due to Herpes simplex virus (type I & II)
- Treatment of viral infections due to Varicella zoster virus (herpes zoster & chicken pox)
- Treatment of Herpes simplex virus infections of the skin and mucous membranes
- Prophylaxis of Herpes simplex infections in immunocompromised patients
Pharmacology
- Synthetic purine derivative
- Interferes with DNA synthesis
- Inhibits viral replication
- Converted to Aciclovir Monophosphate via virus coded thymidine kinase
- Converted to Aciclovir Triphosphate
- Absorption rate from the gastrointestinal tract
- Peak plasma concentration time
- Distribution into body tissues and fluids
- Excretion route through the kidneys
Interaction
- Probenecid interaction
Contraindications
- Hypersensitivity to Aciclovir
Side Effects
- Rash
- Gastrointestinal disturbance
- Rise in bilirubin and liver-related enzymes
- Increase in blood urea and creatinine
- Decrease in hematological indices
- Headache
- Neurological reactions
- Fatigue
Pregnancy and Lactation
- Pregnancy category B
- Caution during nursing
- Risk-benefit assessment during pregnancy
Precautions and Warnings
- Administration in patients with renal impairment
- Dose adjustment based on creatinine clearance
- Neutrophil count monitoring in neonates
Therapeutic Class
- Herpes simplex virus infections
- Varicella-zoster virus infections
Storage Conditions
- Temperature storage requirement
- Protection from light and moisture
- Child-resistant storage