Cpdom 10 mg (Tablet)

Title

• Domperidone 10 mg Tablet

Categories

• Medicine
• Pharmaceuticals
• Gastrointestinal Drugs
• Nausea and Vomiting Relief

Description

• Domperidone is a dopamine antagonist used to treat dyspeptic symptoms, acute nausea and vomiting, Parkinson's disease, and for speeding barium transit in radiological studies. It works by blocking dopamine receptors in the Chemoreceptor Trigger Zone (CTZ) and stomach, enhancing gastric emptying, and regulating gastrointestinal motility.

Dimensions

• Standard tablet size: 10 mg

Color Options

• White tablet, may vary based on brand or manufacturer

Functions

• Relieves dyspeptic symptoms such as epigastric fullness, abdominal pain, and nausea
• Controls acute nausea and vomiting of various origins
• Regulates gastrointestinal motility and tone
• Enhances gastric emptying and antral peristalsis
• Prevents regurgitation of gastric content
• Speeds barium transit in radiological studies

Materials

• Active ingredient: Domperidone
• Inactive ingredients may vary based on manufacturer

Technical Specifications

• Oral dose for adults: 10-20 mg every 6-8 hours daily, max 80 mg daily
• Oral dose for children: 2-4 ml/10 kg body weight every 6-8 hours daily
• Suppository dose for adults: 30-60 mg every 4-8 hours
• Suppository dose for children: Max 30 mg for those weighing 10-25 kg

Design Elements

• Tablet shape: Round or oval
• May have a logo or alphanumeric imprint for identification

Usability Features

• Suitable for oral and rectal administration

Indications

• Relief of dyspeptic symptoms
• Treatment of acute nausea and vomiting
• Management of nausea and vomiting induced by dopamine agonists, radiotherapy, or drug therapy
• Used in Parkinson's disease for dopamine-agonist induced nausea and vomiting
• Speeding barium transit in radiological studies

Contraindications

• Hypersensitivity to domperidone
• Neonates
• Gastrointestinal hemorrhage, obstruction or perforation
• Prolactin releasing pituitary tumor (prolactinoma)

Side Effects

• Transient intestinal cramps
• Rare extrapyramidal phenomena in children and adults
• Possible increase in plasma prolactin level leading to galactorrhoea and gynaecomastia
• Rare allergic reactions like rash and urticaria

Pregnancy & Lactation

• Usage during the first trimester justified by therapeutic benefit
• Excreted in breast milk, caution advised during nursing

Precautions & Warnings

• Caution in children due to risk of extra-pyramidal reactions
• Use with caution in patients with hepatic impairment

Use in Special Populations

• Caution advised in infants due to immature blood-brain barrier
• Use with caution in liver and kidney disorders

Overdose Effects

• Symptoms may include drowsiness, disorientation, and extrapyramidal reactions
• Management includes activated charcoal and close patient observation

Therapeutic Class

• Motility Stimulants
• Dopamine Antagonist
• Prokinetic Drugs

Storage Conditions

• Store below 30°C, protected from light and moisture

Chemical Structure

• Molecular formula: C22H24ClN5O2
• Chemical structure available in product literature

Commonly Asked Questions

• Usage for relief of nausea, vomiting, and indigestion
• Tablet should be taken before meals as per doctor's prescription
• Caution advised when driving or operating machinery
• Avoid alcohol consumption with the tablet
• Inform a doctor if watery diarrhea, fever, or stomach pain persists
• Consult a doctor if usage exceeds 7 days

Related Brands

• Dedom 10 mg (Tablet) - decent-pharma-laboratories-ltd
• Dedom 5 mg/5 ml (Oral Suspension) - decent-pharma-laboratories-ltd
• Deflux 10 mg (Tablet) - beximco-pharmaceuticals-ltd
• Deflux Meltab 10 mg (Dispersible Tablet) - beximco-pharmaceuticals-ltd
• Deflux 5 mg/5 ml (Oral Suspension) - beximco-pharmaceuticals-ltd