Dedom 10 mg (Tablet)
Unit Price: ৳ 1.90 (100's pack: ৳ 190.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Decent pharma laboratories ltd |
| Also available as |
Title and Categories
- Dedom 10 mg Tablet
- Gastrointestinal Medication
- Nausea and Vomiting Relief
- Motility Stimulant
- Dopamine Antagonist
- Prokinetic Drug
Dimensions
- Blister Pack: 10 tablets (1 strip)
Dosage Form
Tablet / Suspension
Color Options
- White
- Pink
Active Ingredient
- Domperidone
Indications
- Relief of dyspeptic symptoms like abdominal pain, fullness, and nausea
- Treatment of acute nausea and vomiting
- Management of nausea and vomiting induced by dopamine-agonist therapy
- Use in speeding barium transit in radiological studies
Pharmacology
- Dopamine antagonist action at the Chemoreceptor Trigger Zone and stomach
- Gastroprokinetic action through blockade of dopamine receptors
- Restoration of normal motility and tone of upper gastrointestinal tract
- Facilitation of gastric emptying and enhancement of peristalsis
Dosage and Administration
- Oral administration 15-30 minutes before meals
- Adults: 10-20 mg every 6-8 hours daily
- Maximum daily dose for adults is 80 mg
- Pediatric doses based on body weight
Interactions
- Antagonism with anticholinergic drugs
- Lowered oral bioavailability when given with antacids and antisecretory drugs
- Metabolic pathway inhibition by CYP3A4 inhibitors
Contraindications
- Known hypersensitivity to domperidone
- Gastrointestinal hemorrhage, obstruction, or perforation
- Prolactin releasing pituitary tumor
Side Effects
- Transient intestinal cramps
- Rare extrapyramidal phenomena
- Possible increase in plasma prolactin level
Pregnancy and Lactation
- Use during first trimester if justified by therapeutic benefit
- Excretion in breast milk at lower concentrations than plasma
- Potential risk to newborns
Precautions and Warnings
- Caution in children due to risk of extrapyramidal reactions
- Use with caution in patients with hepatic impairment
Special Populations
- Infant use with caution and close medical supervision
- Caution in patients with liver or kidney disorders
Overdose Effects
- Symptoms include drowsiness, disorientation, and extrapyramidal reactions
- Recommendations for managing overdosage
Therapeutic Class
Motility Stimulants/Dopamine Antagonist
Storage Conditions
Store below 30°C, Protected from light & moisture
Chemical Structure
Molecular Formula: C22H24ClN5O2
Common Questions
- Used for: Relief of nausea and vomiting
- Quick Tips:
- Helps relieve nausea, vomiting, and indigestion
- May cause dizziness and sleepiness
- Avoid alcohol consumption
- Manage dry mouth as a side effect
- Inform doctor about specific symptoms
- Do not take for longer than 7 days without consulting doctor