Simplovir 400 mg (Tablet)
Unit Price: ৳ 22.00 (2 x 10: ৳ 440.00)
Strip Price: ৳ 220.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Acyclovir oral |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Title
- Aciclovir 200mg Tablets
Categories
- Antiviral Medication
- Herpes Treatment
- Virucidal Agent
Description
- Aciclovir is indicated for the treatment of viral infections due to Herpes simplex virus (type I & II) and Varicella zoster virus (herpes zoster & chicken pox). It is also used for the prophylaxis of Herpes simplex infections in immunocompromised patients.
Dosage and Administration
- Dosage regimen for the treatment of initial herpes simplex: 200 mg 5 times daily usually for 5 days.
- Preventive dosage for adults: 200 mg 4 times daily or 400 mg twice daily, possibly reduced to 200 mg 2 or 3 times daily.
- Dosage for the treatment of herpes zoster (Shingles): 800 mg 5 times daily for 7 days.
- Renal Impairment: Dose reduction recommended for patients with severe renal impairment.
Mode of Action
- Inhibits viral replication by interfering with DNA synthesis
- Converted to Aciclovir Triphosphate, the pharmacologically active form, by intracellular processes
Interaction
- Probenecid reduces Aciclovir excretion and increases plasma concentration and risk of toxicity
Contraindications
- Hypersensitivity to Aciclovir
Side Effects
- Rash
- Gastrointestinal disturbance
- Neurological reactions
- Fatigue
Pregnancy and Lactation
- Pregnancy category B
- Caution advised during nursing
Precautions and Warnings
- Administer with caution in patients with renal impairment
- Regular monitoring of neutrophil count in neonates
Therapeutic Class
- Antiviral Medication for Herpes and Varicella-zoster virus infections
Storage Conditions
- Store below 25°C
- Protect from light and moisture
- Keep out of the reach of children