Deflux 5 mg/ml (Pediatric Drops)
15 ml drop: ৳ 20.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Title
- Deflux 5 mg/ml Drops
Categories
- Medicine
- Gastrointestinal
Description
- Deflux 5 mg/ml Drops is a dopamine antagonist medication used to treat nausea, vomiting, and dyspeptic symptom complex. It helps relieve nausea, vomiting, and indigestion.
Color Options
- Clear liquid
Dosage Form
- Oral suspension
- Tablet
- Pediatric drops
- Suppositories
Dimensions
- N/A
Weight
- N/A
Medication Type
- Prescription
Active Ingredient
- Domperidone
Indications
- Dyspeptic symptom complex
- Gastroesophageal reflux
- Delayed gastric emptying
- Acute nausea and vomiting
- Functional nausea and vomiting
- Nausea and vomiting in Parkinson's disease
- Speeding barium transit in radiological studies
Pharmacology
- Dopamine antagonist
- Blocks dopamine receptors in Chemoreceptor Trigger Zone and stomach
- Gastroprokinetic action
- Restores normal motility and tone of the upper gastrointestinal tract
- Facilitates gastric emptying
- Enhances antral and duodenal peristalsis
- Regulates contraction of the pylorus
Dosage & Administration
- Should be taken 15-30 minutes before meals
- Usual recommended oral dose varies for adults and children
- Uses in dyspeptic symptoms, acute/sub-acute conditions, and rectally in suppositories
Interactions
- Contraindicated with anticholinergic drugs
- Antacids and antisecretory drugs should not be given simultaneously
- Main metabolic pathway through CYP3A4
- Potential interaction with CYP3A4 inhibitors
- Does not potentiate action of neuroleptics and dopamine agonists
Contraindications
- Known hypersensitivity to domperidone
- Neonates
- Gastrointestinal hemorrhage, mechanical obstruction, or perforation
- Prolactin releasing pituitary tumor
Side Effects
- Rare side effects like transient intestinal cramps
- Rare extrapyramidal phenomena
- Possible increase in plasma prolactin level
- Rare allergic reactions such as rash and urticaria
Pregnancy & Lactation
- Should be used with caution during the first trimester of pregnancy
- Excreted in breast milk
- Concentrations in breast milk are lower than plasma
Precautions & Warnings
- Caution in children due to the risk of extrapyramidal reactions
- Caution in patients with hepatic impairment
Use in Special Populations
- Use with caution in infants
- Use with caution in liver disorders
- Use with caution in kidney disorders
Overdose Effects
- Symptoms include drowsiness, disorientation, and extrapyramidal reactions
- Activated charcoal and close observation recommended in case of overdosage
Therapeutic Class
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
Storage Conditions
- Store below 30°C
- Protected from light and moisture
- Keep out of children's reach
Chemical Structure
- Molecular Formula: C22H24ClN5O2
Common Questions
- Used to treat nausea and vomiting
- Helps relieve nausea, vomiting, and indigestion
- May cause dizziness and sleepiness
- Avoid consuming alcohol when taking
- Dry mouth may occur as a side effect
- Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away
- Do not take for longer than 7 days without consulting your doctor