Angesic 10 mg (Tablet)
Unit Price: ৳ 10.00 (30's pack: ৳ 300.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ketorolac tromethamine |
| Company | The white horse pharmaceuticals ltd |
Indications
- short-term management
- moderate to severe acute post-operative pain
- relieve pain
- inflammation
- light sensitivity
- ocular surgery
- eye inflammation
- redness
- seasonal allergies
Description
- pyrrolo-pyrrole group
- nonsteroidal anti-inflammatory drug
- inhibits synthesis of prostaglandins
- peripherally acting analgesic
- highly protein bound
- metabolized in liver
- urine excretion
Pharmacology
- potent analgesic
- non-steroidal anti-inflammatory drugs (NSAIDs)
- inhibits cyclooxygenase enzyme system
- minimal anti-inflammatory effect
- prostaglandin synthesis
Dosage & Administration
- Tablet: 10 mg every 4-6 hours
- short-term use (up to 7 days)
- not recommended for chronic use
- Injection: single or multiple doses
- IV bolus over 15 seconds
- IM administration slowly and deeply
- onset within 30 minutes
- maximum effect in 1 to 2 hours
- duration 4 to 6 hours
- Eye Drops: 1 drop in each eye 4 times daily
Interaction
- Increase side effects with other NSAIDs or aspirin
- Enhance anti-coagulant effect with anti-coagulants
- Reduce anti-hypertensive effect with Beta Blocker
- Increase risk of renal impairment with ACE Inhibitors
- Enhance toxicity of methotrexate
Contraindications
- hypersensitivity to drug or other NSAIDs
- age below 16 years
- prophylactic analgesic before surgery
Side Effects
- nausea
- vomiting
- gastro-intestinal bleeding
- melana
- peptic ulcer
- pancreatitis
- anxiety
- drowsiness
- headache
- excessive thirst
- fatigue
- bradycardia
- hypertension
- palpitation
- chest pain
- infertility in female
- pulmonary edema
Pregnancy & Lactation
- Pregnancy category C
- avoid in pregnancy and lactation
- weigh potential benefits against possible risks to fetus
Precautions & Warnings
- Caution for patients over 65 years
- active or suspected peptic ulcer
- gastrointestinal bleeding
- asthma
- liver dysfunction
- discontinue use in evidence of corneal epithelial breakdown
- closely monitor corneal health
- avoid use with contact lenses
Therapeutic Class
- Rheumatoid Arthritis
- Non-Opioid Analgesics
Storage Conditions
- Keep in dry place
- away from light and heat
- keep out of reach of children
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