Detolac 10 mg (Tablet)

Unit Price: ৳ 8.00 (5 x 10: ৳ 400.00)
Strip Price: ৳ 80.00

Medicine Details

Category Details
Generic Ketorolac tromethamine
Company Desh pharmaceuticals ltd

Indications

  • Management of moderate to severe acute post-operative pain
  • Relief of pain, inflammation, and light sensitivity after ocular surgery
  • Decrease eye inflammation or redness caused by seasonal allergies

Description

  • Drug of pyrrolo-pyrrole group of NSAID
  • Chemical name: 5 benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid, compound with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
  • Inhibits synthesis of prostaglandins
  • Peripherally acting analgesic

Pharmacology

  • Potent analgesic of the NSAIDs
  • Inhibits cyclooxygenase enzyme system
  • Minimal anti-inflammatory effect at analgesic dose

Dosage & Administration

  • Recommended tablet dose: 10 mg every 4-6 hours for short-term use
  • Injection may be used for acute pain management post-operatively
  • Dosage varies by age and condition

Interaction

  • Increase in side effects with other NSAIDs or aspirin
  • Enhanced anticoagulant effect with anticoagulants
  • Reduction in antihypertensive effect with beta blockers
  • Increased risk of renal impairment with ACE inhibitors
  • Enhanced toxicity of methotrexate

Contraindications

  • Hypersensitivity to Ketorolac or other NSAIDs
  • Not for use in children under 16 years of age
  • Contraindicated as prophylactic analgesic before surgery

Side Effects

  • Nausea, vomiting
  • Gastrointestinal bleeding, peptic ulcer, pancreatitis
  • Anxiety, drowsiness, headache
  • Excessive thirst, fatigue
  • Bradycardia, hypertension, palpitation, chest pain
  • Infertility in females, pulmonary edema

Pregnancy & Lactation

  • FDA Pregnancy category C
  • Avoid in pregnancy and lactation unless benefits outweigh risks

Precautions & Warnings

  • Caution in patients over 65 years
  • Caution in patients with peptic ulcer, gastrointestinal bleeding, asthma, liver dysfunction
  • Monitoring for corneal health with topical NSAID use

Therapeutic Class

  • Used for Rheumatoid Arthritis
  • Non-Opioid Analgesics

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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