Degut 10 mg (Tablet)
Unit Price: ৳ 2.00 (6 x 15: ৳ 180.00)
Strip Price: ৳ 30.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Delta pharma ltd |
Indications
- Dyspeptic symptom complex
- Delayed gastric emptying
- Gastroesophageal reflux
- Esophagitis
- Non-ulcer dyspepsia
- Acute nausea and vomiting
- Parkinson's disease
- Radiological studies
Pharmacology
- Dopamine antagonist
- ChemoreceptorTrigger Zone (CTZ) blocker
- Gastroprokinetic action
- Influence on gastrointestinal motility
- Weak penetration of blood-brain barrier
- Restores normal motility and tone of upper gastrointestinal tract
- Facilitates gastric emptying
- Enhances antral and duodenal peristalsis
- Regulates contraction of the pylorus
- Increases esophageal peristalsis
- Enhances lower esophageal sphincter pressure
Dosage and administration
- Oral dosing for adults
- Oral dosing for children
- Rectal dosing for adults
- Rectal dosing for children
- Maximum daily dosage
- Timing of dosage relative to meals
Interactions
- Anticholinergic drug interactions
- Antacids and antisecretory drug interactions
- Metabolism through CYP3A4
- Inhibition of CYP3A4 by other drugs
- Potential influence on absorption of concomitantly orally administered drugs
- Neuroleptics
- Dopaminergic agonists
Contraindications
- Known hypersensitivity
- Neonatal use
- Gastrointestinal hemorrhage
- Mechanical obstruction
- Perforation
- Prolactin releasing pituitary tumor
Side effects
- Transient intestinal cramps
- Extrapyramidal phenomena
- Increase in plasma prolactin level
- Galactorrhoea
- Gynaecomastia
- Allergic reactions
- Rash
- Urticaria
Pregnancy and lactation
- Use in first trimester of pregnancy
- Excretion in breast milk
- Domperidone concentrations in breast milk
- Effects on the newborn
- Effects on ability to drive and use machines
Precautions and warnings
- Caution in children
- Risk of extra-pyramidal reactions in young children
- Metabolism in the liver
- Use in hepatic impairment
Use in special populations
- Use in infants
- Immature blood-brain barrier in infants
- Use in liver disorders
- Use in kidney disorders
- Renal insufficiency
Overdose effects
- Drowsiness
- Disorientation
- Extrapyramidal reactions
- Activated charcoal administration
Therapeutic class
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
Storage conditions
- Temperature storage
- Protection from light
- Protection from moisture
- Keep out of children's reach
Chemical structure
- Molecular formula
- C22H24ClN5O2
- Chemical structure image (link)
Commonly asked questions
- Usage of Degut 10 mg Tablet
- Quick tips for usage
- Relieving nausea, vomiting, and indigestion
- Dizziness and sleepiness as side effects
- Alcohol consumption caution
- Dry mouth as a side effect
- Watery diarrhea, fever, or stomach pain reporting