Eket 30 mg/ml (IM/IV Injection)
1 ml ampoule: ৳ 50.00 (5's pack: ৳ 250.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ketorolac tromethamine |
| Company | Edruc limited |
| Also available as |
Title and Category
- Eket Ophthalmic Solution
- Nonsteroidal Anti-inflammatory Drug (NSAID)
- Rheumatoid Arthritis Medication
- Non-Opioid Analgesic
Indications
- Short-term management of moderate to severe acute post-operative pain
- Relief of pain, inflammation, and light sensitivity after ocular surgery
- Decreasing eye inflammation or redness caused by seasonal allergies
Description
- Chemical composition: 5 benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid, compound with 2 - amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
- Inhibition of prostaglandin synthesis
- Biological activity associated with the S-form
- Linear pharmacokinetic property
- High protein binding
- Metabolized in the liver
- Excretion in the urine
Pharmacology
- Potent analgesic NSAID
- Inhibition of cyclooxygenase enzyme system
- Minimal anti-inflammatory effect at analgesic dose
Dosage & Administration
- Tablet recommended dose: 10 mg every 4-6 hours
- Tablet not recommended for chronic use or doses exceeding 40 mg/day
- Injection for management of moderately severe, acute pain
- Single-dose treatment for adult and pediatric patients
- Multiple-dose treatment in different patient populations
- Ophthalmic solution dosage: 1 drop in each eye 4 times daily
Interactions
- Increased side effects with other NSAIDs or aspirin
- Enhanced anti-coagulant effect with anticoagulants
- Reduced anti-hypertensive effect with beta blockers
- Increased risk of renal impairment with ACE inhibitors
- Enhanced toxicity of methotrexate
Contraindications
- Hypersensitivity to Ketorolac or other NSAIDs
- Children under 16 years of age
- Prophylactic analgesic use before surgery
Side Effects
- Nausea
- Vomiting
- Gastrointestinal bleeding
- Melena
- Peptic ulcer
- Pancreatitis
- Anxiety
- Drowsiness
- Headache
- Excessive thirst
- Fatigue
- Bradycardia
- Hypertension
- Palpitation
- Chest pain
- Infertility in females
- Pulmonary edema
Pregnancy & Lactation
- US FDA Pregnancy category: C
- Avoidance in pregnancy and lactation unless benefits outweigh risks to fetus
Precautions & Warnings
- Caution in patients over 65 years
- Caution in patients with peptic ulcer, gastrointestinal bleeding, asthma, or liver dysfunction
- Discontinue use if evidence of corneal epithelial breakdown
- Avoid administration while wearing contact lenses
Therapeutic Class
- Rheumatoid Arthritis Medication
- Non-Opioid Analgesics
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children