Emodol 30 mg/ml (IM/IV Injection)
1 ml ampoule: ৳ 58.00 (1 x 5: ৳ 290.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ketorolac tromethamine |
| Company | Jayson pharmaceuticals ltd |
| Also available as |
Indications
- Short-term management of moderate to severe acute post-operative pain
- Relief of pain, inflammation, and light sensitivity after ocular surgery
- Decrease in eye inflammation or redness caused by seasonal allergies
Description
- Drug of pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drug (NSAID)
- Chemical name - 5 benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid, compound with 2 - amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
- Inhibits synthesis of prostaglandins
- Peripherally acting analgesic
- Biological activity associated with the S-form
- Linear pharmacokinetic property
- Highly protein bound
- Metabolized in the liver
- Excretion in urine
Pharmacology
- Potent analgesic of the non-steroidal anti-inflammatory drugs (NSAIDs)
- Inhibits the cyclooxygenase enzyme system
- Minimal anti-inflammatory effect at its analgesic dose
Dosage & Administration
- Tablet recommended dose: 10 mg every 4-6 hours
- Injection for postoperative pain management
- Different doses for patients of different age groups
- Maximum daily doses
- Eye drops administration
Interaction
- Increase in side effects with other NSAIDs or aspirin
- Enhanced anti-coagulant effect with anti-coagulants
- Reduced anti-hypertensive effect with beta blockers
- Increased risk of renal impairment with ACE inhibitors
- Enhanced toxicity of methotrexate
Contraindications
- Hypersensitivity to drug or other NSAIDs
- Children under 16 years of age
- Prophylactic analgesic before surgery
Side Effects
- Nausea
- Vomiting
- Gastro-intestinal bleeding
- Melena
- Peptic ulcer
- Pancreatitis
- Anxiety
- Drowsiness
- Headache
- Excessive thirst
- Fatigue
- Bradycardia
- Hypertension
- Palpitation
- Chest pain
- Infertility in females
- Pulmonary edema
Pregnancy & Lactation
- FDA Pregnancy category C
- Avoidance in pregnancy and lactation unless benefits outweigh risks
Precautions & Warnings
- Patients over the age of 65 years
- Patients with active or suspected peptic ulcer or gastrointestinal bleeding
- Patients with asthma and liver dysfunction
- Eye drops precautions for patients with corneal issues
- Avoidance while wearing contact lenses
Therapeutic Class
- Drugs used for Rheumatoid Arthritis
- Non-Opioid Analgesics
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children