Kenodol 30 mg/ml (IM/IV Injection)

1 ml ampoule: ৳ 55.00 (1 x 6: ৳ 330.00)

Medicine Details

Category Details
Generic Ketorolac tromethamine
Company Rangs pharmaceuticals ltd
Also available as
Kenodol 10 mg tablet Kenodol 60 mg injection

Indications

  • Short-term management of moderate to severe acute post-operative pain
  • Relief of pain, inflammation, and light sensitivity after ocular surgery
  • Decrease eye inflammation or redness caused by seasonal allergies

Description

  • Belongs to the pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drugs (NSAID)
  • Chemically known as 5 benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid, compound with 2 - amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
  • Inhibits synthesis of prostaglandins
  • Peripherally acting analgesic
  • Highly protein bound
  • Largely metabolized in the liver

Pharmacology

  • Potent analgesic
  • Inhibits the cyclooxygenase enzyme system
  • Minimal anti-inflammatory effect at analgesic dose

Dosage & Administration

  • Tablet recommended dose: 10 mg every 4-6 hours for short-term use
  • Injection may be used as single or multiple doses for moderately severe, acute pain
  • Analgesic effect begins within 30 minutes with maximum effect in 1 to 2 hours after dosing
  • Recommended eye drops administration: 1 drop in each eye 4 times daily

Interaction

  • Interacts with other NSAIDs or aspirin, anti-coagulants, beta blockers, ACE inhibitors, and methotrexate

Contraindications

  • Hypersensitivity to this drug or other NSAIDs
  • Use in children under 16 years of age
  • Prophylactic analgesic use before surgery

Side Effects

  • Nausea
  • Vomiting
  • Gastro-intestinal bleeding
  • Melena
  • Peptic ulcer
  • Pancreatitis
  • Anxiety
  • Drowsiness
  • Headache
  • Excessive thirst
  • Fatigue
  • Bradycardia
  • Hypertension
  • Palpitation
  • Chest pain
  • Infertility in female
  • Pulmonary edema

Pregnancy & Lactation

  • Pregnancy category C
  • Avoided in pregnancy and lactation unless benefits outweigh risks

Precautions & Warnings

  • Exercise caution in patients over the age of 65 years
  • Exercise caution in patients with active or suspected peptic ulcer, gastrointestinal bleeding, asthma, and liver dysfunction
  • Discontinue use of topical NSAIDs in patients with evidence of corneal epithelial breakdown

Therapeutic Class

  • Drugs used for Rheumatoid Arthritis
  • Non-Opioid Analgesics

Storage Conditions

  • Store in a dry place away from light and heat
  • Keep out of the reach of children

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