Kerolac 10 mg (Tablet)

Unit Price: ৳ 11.00 (2 x 10: ৳ 220.00)
Strip Price: ৳ 110.00

Medicine Details

Category Details
Generic Ketorolac tromethamine
Company Gaco pharmaceuticals ltd

Indications

  • Short-term management of moderate to severe acute post-operative pain
  • Relief of pain, inflammation, and light sensitivity after ocular surgery
  • Decrease eye inflammation or redness caused by seasonal allergies

Description

  • Belongs to the pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drugs (NSAID)
  • Inhibits synthesis of prostaglandins
  • Biological activity associated with the S-form
  • Highly protein bound
  • Metabolized in the liver
  • Products of metabolism and some unchanged drugs excreted in the urine

Pharmacology

  • Potent analgesic of the non-steroidal anti-inflammatory drugs (NSAIDs)
  • Inhibits the cyclooxygenase enzyme system
  • Demonstrates minimal anti-inflammatory effect at its analgesic dose

Dosage & Administration

  • Tablet: Recommended dose is 10 mg every 4-6 hours for short-term use
  • Injection: Administered single or multiple doses for the management of moderately severe, acute pain
  • Onset of analgesic effect within 30 minutes with maximum effect in 1 to 2 hours
  • Duration of analgesic effect is usually 4 to 6 hours

Interaction

  • With other NSAIDs or aspirin: Increases the side effects of Kerolac
  • With anti-coagulants: Enhances anti-coagulant effect
  • With Beta Blocker: Reduces the anti-hypertensive effect
  • With ACE Inhibitors: Increases the risk of renal impairment
  • With Methotrexate: Enhances the toxicity of methotrexate

Contraindications

  • Hypersensitivity to Ketorolac or other NSAIDs
  • Children under 16 years of age
  • Prophylactic analgesic before surgery

Side Effects

  • Nausea
  • Vomiting
  • Gastro-intestinal bleeding
  • Melana
  • Peptic ulcer
  • Pancreatitis
  • Anxiety
  • Drowsiness
  • Headache
  • Excessive thirst
  • Fatigue
  • Bradycardia
  • Hypertension
  • Palpitation
  • Chest pain
  • Infertility in females
  • Pulmonary edema

Pregnancy & Lactation

FDA Pregnancy category C; should be avoided unless benefits outweigh risks

Precautions & Warnings

  • Caution in patients over 65 years
  • Caution in patients with active or suspected peptic ulcer, gastrointestinal bleeding, asthma, and liver dysfunction
  • In case of corneal epithelial breakdown, discontinue use of topical NSAIDs

Therapeutic Class

  • Rheumatoid Arthritis Drugs
  • Non-Opioid Analgesics

Storage Conditions

Keep in a dry place away from light and heat; keep out of reach of children

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