Ketonic 10 mg (Tablet)
Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ketorolac tromethamine |
| Company | Eskayef pharmaceuticals ltd |
| Also available as |
Indications
- Short-term management of post-operative pain
- Relieves pain, inflammation, and light sensitivity after ocular surgery
- Decreases eye inflammation or redness caused by seasonal allergies
Drug Group
Pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drug (NSAID)
Chemical Composition
5 benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid, compound with 2 - amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
Mode of Action
Inhibits synthesis of prostaglandins and acts as a peripherally acting analgesic
Pharmacokinetic Property
Linear, highly protein bound, largely metabolized in liver, excreted in urine
Dosage Recommendations
- Tablet: 10 mg every 4-6 hours for short-term use (up to 7 days)
- Injection: Single or multiple doses for moderately severe, acute pain
- Eye Drops: 1 drop in each eye 4 times daily for adult use
Interaction
- Increased side effects with other NSAIDs or aspirin
- Enhanced anti-coagulant effect with anti-coagulants
- Reduced anti-hypertensive effect with Beta Blocker
- Increased risk of renal impairment with ACE Inhibitors
- Enhanced toxicity of methotrexate
Contraindications
- Hypersensitivity to the drug or other NSAIDs
- Children under 16 years of age
- Prophylactic analgesic before surgery
Side Effects
- Nausea
- Vomiting
- Gastro-intestinal bleeding
- Melana
- Peptic ulcer
- Pancreatitis
- Anxiety
- Drowsiness
- Headache
- Excessive thirst
- Fatigue
- Bradycardia
- Hypertension
- Palpitation
- Chest pain
- Infertility in females
- Pulmonary edema
Pregnancy & Lactation
Avoid in pregnancy and lactation unless the potential benefits outweigh the possible risks to the fetus
Precautions & Warnings
- Exercise caution in patients over the age of 65 years
- Caution in patients with active or suspected peptic ulcer, gastrointestinal bleeding, asthma, and liver dysfunction
- Discontinue use of topical NSAIDs in patients with evidence of corneal epithelial breakdown
- Avoid administering while wearing contact lenses (for eye drops)
Therapeutic Class
- Rheumatoid Arthritis
- Non-Opioid Analgesics
Storage Conditions
Keep in a dry place away from light and heat, and out of the reach of children