Ketorolac 10 mg (Tablet)
Unit Price: ৳ 10.00 (40's pack: ৳ 400.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ketorolac tromethamine |
| Company | Bristol pharmaceuticals ltd |
Indications
- Short-term management of moderate to severe acute post-operative pain
- Relief of pain, inflammation, and light sensitivity after ocular surgery
- Decrease eye inflammation or redness caused by seasonal allergies
Description
- Pyrrolo-pyrrole group drug
- Chemical composition: 5 benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid, compound with 2 - amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
- Inhibits synthesis of prostaglandins
- Peripherally acting analgesic
- Metabolized in the liver
Pharmacology
- Potent analgesic
- Inhibits cyclooxygenase enzyme system
- Demonstrates minimal anti-inflammatory effect at analgesic dose
Dosage & Administration
- Tablet recommended dose: 10 mg every 4-6 hours (short-term use)
- Injection recommended doses for different age groups and conditions
- Eye drops recommended dose: 1 drop in each eye 4 times daily
Interaction
- Other NSAIDs or aspirin: Increase side effects
- Anti-coagulants: Enhance anti-coagulant effect
- Beta Blocker: Reduce anti-hypertensive effect
- ACE Inhibitors: Increase risk of renal impairment
- Methotrexate: Enhance toxicity of methotrexate
Contraindications
- Hypersensitivity to Ketorolac or other NSAIDs
- Not for use in children under 16 years of age
- Not for prophylactic analgesic use before surgery
Side Effects
- Nausea
- Vomiting
- Gastro-intestinal bleeding
- Melena
- Peptic ulcer
- Pancreatitis
- Anxiety
- Drowsiness
- Headache
- Excessive thirst
- Fatigue
- Bradycardia
- Hypertension
- Palpitation
- Chest pain
- Infertility in females
- Pulmonary edema
Pregnancy & Lactation
- US FDA Pregnancy category: C
- Avoid use in pregnancy and lactation unless benefits outweigh risks
Precautions & Warnings
- Caution in patients over 65 years
- Caution in patients with peptic ulcer, gastrointestinal bleeding, asthma, and liver dysfunction
- Discontinue use if evidence of corneal epithelial breakdown
Therapeutic Class
- Rheumatoid Arthritis
- Non-Opioid Analgesics
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children