Ketovir 10 mg (Tablet)

Unit Price: ৳ 10.00 (20's pack: ৳ 200.00)

Medicine Details

Category Details
Generic Ketorolac tromethamine
Company Virgo pharmaceuticals ltd

Indications

  • Management of moderate to severe acute post-operative pain
  • Relieves pain, inflammation, and light sensitivity after ocular surgery
  • Decreases eye inflammation or redness caused by seasonal allergies

Description

  • Belongs to the pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drug (NSAID)
  • Chemical name: 5 benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid, compound with 2 - amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
  • Inhibits synthesis of prostaglandins
  • Peripherally acting analgesic
  • Highly protein bound
  • Metabolized in the liver
  • Excreted in the urine

Pharmacology

  • Potent analgesic of the non-steroidal anti-inflammatory drugs (NSAIDs)
  • Inhibits the cyclooxygenase enzyme system
  • Demonstrates minimal anti-inflammatory effect at its analgesic dose

Dosage & Administration

  • Tablet: Recommended dose is 10 mg every 4-6 hours for short-term use (up to 7 days)
  • Injection: May be used for the management of moderately severe, acute pain
  • Eye Drops: Adults: 1 drop in each eye 4 times daily

Interaction

  • Other NSAIDs or aspirin increase the side effects
  • Anti-coagulants enhance anti-coagulant effect
  • Beta Blocker reduce the anti-hypertensive effect
  • ACE Inhibitors increase the risk of renal impairment
  • Methotrexate enhances the toxicity of methotrexate

Contraindications

  • Hypersensitivity to this drug or other NSAIDs
  • Not recommended for use in children under 16 years of age
  • Contraindicated as prophylactic analgesic before surgery

Side Effects

  • Nausea
  • Vomiting
  • Gastro-intestinal bleeding
  • Melana
  • Peptic ulcer
  • Pancreatitis
  • Anxiety
  • Drowsiness
  • Headache
  • Excessive thirst
  • Fatigue
  • Bradycardia
  • Hypertension
  • Palpitation
  • Chest pain
  • Infertility in female
  • Pulmonary edema

Pregnancy & Lactation

Pregnancy category is C. Avoid use unless benefits outweigh risks to the fetus

Precautions & Warnings

  • Caution in patients over the age of 65 years
  • Caution in patients with active or suspected peptic ulcer or gastrointestinal bleeding
  • Caution in patients with asthma and liver dysfunction
  • Discontinue use of topical NSAIDs in patients with evidence of corneal epithelial breakdown

Therapeutic Class

Rheumatoid Arthritis, Non-Opioid Analgesics

Storage Conditions

Keep in a dry place away from light and heat. Keep out of the reach of children

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