Ketromin 10 mg (Tablet)
Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ketorolac tromethamine |
| Company | Pacific pharmaceuticals ltd |
| Also available as |
Title and Categories
- Ketromin
- Nonsteroidal Anti-Inflammatory Drug (NSAID)
- Rheumatoid Arthritis Medication
- Ophthalmic Solution
- Analgesic Drug
Indications
- Management of moderate to severe acute post-operative pain
- Relief of pain and inflammation after ocular surgery
- Decrease eye inflammation or redness caused by seasonal allergies
Description
- Chemical composition: 5 benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid, compound with 2 - amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
- Biological activity associated with the S-form
- Pharmacokinetic property is linear
- Metabolized in the liver
- Metabolites and unchanged drug excreted in the urine
Mode of Action
- Inhibition of prostaglandin synthesis
- Minimal anti-inflammatory effect at analgesic dose
Dosage & Administration
- Tablet recommended dose: 10 mg every 4-6 hours for up to 7 days
- Injection for moderate to severe acute pain management
- IV bolus administration over at least 15 seconds
- Duration of analgesic effect: 4 to 6 hours
Interaction
- Increase in side effects with other NSAIDs or aspirin
- Enhanced anti-coagulant effect with anti-coagulants
- Reduction in anti-hypertensive effect with Beta Blockers
- Increased risk of renal impairment with ACE Inhibitors
- Enhanced toxicity of methotrexate
Contraindications
- Hypersensitivity to Ketorolac or other NSAIDs
- Use not recommended for children under 16 years
- Contraindicated as prophylactic analgesic before surgery
Side Effects
- Nausea
- Vomiting
- Gastro-intestinal bleeding
- Melena
- Peptic ulcer
- Pancreatitis
- Anxiety
- Drowsiness
- Headache
- Excessive thirst
- Fatigue
- Bradycardia
- Hypertension
- Palpitation
- Chest pain
- Infertility in females
- Pulmonary edema
Pregnancy & Lactation
- FDA Pregnancy category: C
- Avoid use during pregnancy and lactation unless benefits outweigh risks
Precautions & Warnings
- Caution in patients over 65 years
- Caution in patients with active or suspected peptic ulcer or gastrointestinal bleeding
- Caution in patients with asthma and liver dysfunction
- Discontinue use of topical NSAIDs in patients with corneal epithelial breakdown
- Avoid administration while wearing contact lenses
Therapeutic Class
- Rheumatoid Arthritis Medication
- Non-Opioid Analgesics
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of reach of children