Domidon 5 mg/5 ml (Oral Suspension)

60 ml bottle: ৳ 35.00

Medicine Details

Category Details
Generic Domperidone maleate
Company Ziska pharmaceuticals ltd
Also available as

Title

  • Domidon 5mg/5ml Suspension

Categories

  • Medicine
  • Gastrointestinal
  • Antiemetic
  • Prokinetic

Description

  • Dopamine antagonist medication used to treat nausea, vomiting, and dyspeptic symptoms

Color Options

Clear liquid

Packaging Dimensions

  • 10cm x 6cm x 15cm

Weight

150 grams

Dosage Form

Suspension

Age Group

  • Adults
  • Children

Age Range

  • Adults: 18 years and above
  • Children: 1-18 years

Dosage Strength

5mg/5ml

Number of Tablets per Bottle

120

Ingredients

  • Domperidone

Dosage Administration

  • Recommended Time: 15-30 minutes before meals
  • Frequency: Every 6-8 hours
  • Max Daily Dose: 80mg for adults
  • Administration Methods:
    • Oral
    • Rectal

Indications

  • Dyspeptic symptom complex
  • Delayed gastric emptying
  • Gastroesophageal reflux
  • Acute nausea and vomiting
  • Parkinson's disease
  • Radiological studies

Pharmacology

  • Mode of Action: Dopamine antagonist
  • Target Receptors:
    • Chemoreceptor Trigger Zone
    • Stomach
    • Gastrointestinal tract
  • Effects:
    • Gastroprokinetic
    • Enhances antral and duodenal peristalsis
    • Regulates pylorus contraction
    • Increases esophageal peristalsis
    • Restores normal motility

Interaction

  • Antagonistic Drugs:
    • Anticholinergics
  • CYP3A4 Inhibitors:
    • Azole antifungals
    • Macrolide antibiotics
    • HIV protease inhibitors
  • Compatible Drugs:
    • Neuroleptics
    • Dopaminergic agonists

Contraindications

  • Hypersensitivity to domperidone
  • Neonates
  • Gastrointestinal hemorrhage
  • Mechanical obstruction or perforation
  • Prolactin releasing pituitary tumor

Side Effects

  • Transient intestinal cramps
  • Extrapyramidal phenomena
  • Increased plasma prolactin level
  • Rare allergic reactions

Pregnancy & Lactation

  • Use during first trimester if justified by therapeutic benefit
  • Excretion in breast milk
  • Caution for nursing mothers

Precautions & Warnings

  • Caution in children
  • Caution in hepatic impairment

Special Populations

  • Infants: Caution and close medical supervision
  • Liver Disorders: Caution
  • Kidney Disorders: Dosage adjustment may be needed

Overdose Effects

  • Drowsiness
  • Disorientation
  • Extrapyramidal reactions

Therapeutic Class

Motility Stimulants/Dopamine antagonist

Storage Conditions

  • Below 30°C
  • Protected from light & moisture

Chemical Structure

  • Molecular Formula: C22H24ClN5O2
  • Image: https://medex.com.bd/storage/res/g-res-380-domperidone-maleate-chemical-structure-4Q6P0Z8laWrV7xnOkSMm.svg

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