Toramax 10 mg (Tablet)
Unit Price: ৳ 30.00 (2 x 10: ৳ 600.00)
Strip Price: ৳ 300.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ketorolac tromethamine |
| Company | Popular pharmaceuticals ltd |
| Also available as |
Indications
- Management of moderate to severe acute post-operative pain
- Relief of pain, inflammation, and light sensitivity after ocular surgery
- Decreasing eye inflammation or redness caused by seasonal allergies
Description
- Pyrrolo-pyrrole group nonsteroidal anti-inflammatory drug (NSAID)
- Chemical name: 5 benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid, compound with 2 - amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
- Inhibits synthesis of prostaglandins
- Peripherally acting analgesic
- Highly protein bound
- Metabolized in the liver
- Biological activity associated with S-form
- Linear pharmacokinetic property
Pharmacology
- Potent analgesic
- Inhibits cyclooxygenase enzyme system
- Minimal anti-inflammatory effect at analgesic dose
Dosage & Administration
- Tablet recommended dose: 10 mg every 4-6 hours for short-term use (up to 7 days)
- Injection for various conditions including postoperative pain
- Single and multiple dose treatment guidelines for different age groups
- Maximum daily doses for different patient populations
Interaction
- Increased side effects with other NSAIDs or aspirin
- Enhanced anti-coagulant effect with anti-coagulants
- Reduced anti-hypertensive effect with beta blockers
- Increased risk of renal impairment with ACE Inhibitors
- Enhanced toxicity of methotrexate
Contraindications
- Hypersensitivity to drug or other NSAIDs
- Children under 16 years of age
- Prophylactic analgesic use before surgery
Side Effects
- Nausea
- Vomiting
- Gastro-intestinal bleeding
- Melena
- Peptic ulcer
- Pancreatitis
- Anxiety
- Drowsiness
- Headache
- Excessive thirst
- Fatigue
- Bradycardia
- Hypertension
- Palpitation
- Chest pain
- Infertility in females
- Pulmonary edema
Pregnancy & Lactation
- US FDA Pregnancy category C
- Avoidance in pregnancy and lactation unless benefits outweigh risks
Precautions & Warnings
- Caution in patients over 65 years
- Caution in patients with active or suspected peptic ulcer or gastrointestinal bleeding
- Caution in patients with asthma and liver dysfunction
- Discontinuation and monitoring for corneal health in patients with corneal epithelial breakdown
- Avoidance in patients wearing contact lenses
Therapeutic Class
- Drugs used for Rheumatoid Arthritis
- Non-Opioid Analgesics
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children