Oradol 30 mg/ml (IM/IV Injection)
1 ml ampoule: ৳ 55.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ketorolac tromethamine |
| Company | Aristopharma ltd |
| Also available as |
Title
Oradol Medicine
Categories
- Pain Management
- Ophthalmic Solutions
- NSAIDs
- Analgesics
- Therapeutic Drugs
Description
- Effective for short-term management of moderate to severe acute post-operative pain
- Inhibits prostaglandin synthesis
- Potent analgesic and anti-inflammatory effect
- Metabolized in the liver
- Highly protein bound
- Linear pharmacokinetic property
Indications
- Short-term management of moderate to severe acute post-operative pain
- Relief of pain, inflammation, and light sensitivity after ocular surgery
- Decrease eye inflammation or redness caused by seasonal allergies
Pharmacology
- Potent analgesic of the non-steroidal anti-inflammatory drugs (NSAIDs)
- Inhibits the cyclooxygenase enzyme system
- Minimal anti-inflammatory effect at analgesic dose
Dosage and administration
- Recommended dosage of 10 mg every 4-6 hours (tablet)
- Single or multiple doses for postoperative pain management (injection)
- Specific dosages for different age groups and conditions
- Eye drops: 1 drop in each eye 4 times daily
Interaction
- Increase in side effects with other NSAIDs or aspirin
- Enhanced anti-coagulant effect with anti-coagulants
- Reduced anti-hypertensive effect with beta blockers
- Increased risk of renal impairment with ACE inhibitors
- Enhanced toxicity of methotrexate
Contraindications
- Hypersensitivity to Ketorolac or other NSAIDs
- Children under 16 years of age
- Prophylactic analgesic before surgery
Side effects
- Nausea
- Vomiting
- Gastro-intestinal bleeding
- Melena
- Peptic ulcer
- Pancreatitis
- Anxiety
- Drowsiness
- Headache
- Excessive thirst
- Fatigue
- Bradycardia
- Hypertension
- Palpitation
- Chest pain
- Infertility in females
- Pulmonary edema
Pregnancy and lactation
- FDA Pregnancy category C
- Avoid in pregnancy and lactation unless benefits outweigh risks to the fetus
Precautions and warnings
- Caution in patients over 65 years
- Caution in patients with peptic ulcer, gastrointestinal bleeding, asthma, and liver dysfunction
- Discontinue use in case of corneal epithelial breakdown (eye drops)
- Avoid use with contact lenses (eye drops)
Therapeutic class
- Rheumatoid Arthritis Drugs
- Non-Opioid Analgesics
Storage conditions
- Store in a dry place away from light and heat
- Keep out of the reach of children
Chemical composition
- Pyrrolo-pyrrole group of NSAIDs
- Chemical name: 5-benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid, compound with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
- Biological activity associated with the S-form
- Metabolized and excreted in the urine