Orc 10 mg (Tablet)
Unit Price: ৳ 11.60 (3 x 10: ৳ 348.00)
Strip Price: ৳ 116.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ketorolac tromethamine |
| Company | Navana pharmaceuticals ltd |
Indications
- Short-term management of moderate to severe acute post-operative pain
- Relieve pain, inflammation, and light sensitivity after ocular surgery
- Decrease eye inflammation or redness caused by seasonal allergies
Therapeutic Class
- Rheumatoid Arthritis drugs
- Non-Opioid Analgesics
Pharmacology
- Inhibits synthesis of prostaglandins
- Minimal anti-inflammatory effect at analgesic dose
Drug of pyrrolo-pyrrole group
1
Chemical composition
5 benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid, compound with 2 - amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
Biological activity associated with S-form
1
Pharmacokinetic property
Linear, highly protein bound
Metabolized in liver
1
Excretion
- Metabolites and some unchanged drugs excreted in the urine
Dosage & Administration
- Tablet: Recommended dose is 10 mg every 4-6 hours for short-term use (up to 7 days)
- Injection: Single or multiple doses, IV bolus over no less than 15 seconds, IM administration given slowly and deeply into the muscle, analgesic effect begins within 30 minutes
- Eye Drops: Adults: 1 drop in each eye 4 times daily
Dosage for different age groups and conditions
1
Interaction
- Other NSAIDs or aspirin increase side effects
- Anti-coagulants enhance anti-coagulant effect
- Beta Blocker reduce anti-hypertensive effect
- ACE Inhibitors increase risk of renal impairment
- Methotrexate enhance toxicity
Contraindications
- Hypersensitivity to this drug or other NSAIDs
- Children under 16 years of age
- Prophylactic analgesic before surgery
Side Effects
- Nausea
- Vomiting
- Gastro-intestinal bleeding
- Melena
- Peptic ulcer
- Pancreatitis
- Anxiety
- Drowsiness
- Headache
- Excessive thirst
- Fatigue
- Bradycardia
- Hypertension
- Palpitation
- Chest pain
- Infertility in female
- Pulmonary edema
Pregnancy & Lactation
- FDA Pregnancy category: C
- Recommendation: Avoid unless potential benefits outweigh the possible risks to the fetus
Precautions & Warnings
- Exercise caution in patients over 65 years
- Active or suspected peptic ulcer or gastrointestinal bleeding
- Asthma and liver dysfunction
- Discontinue use of topical NSAIDs in patients with corneal epithelial breakdown
- Do not administer while wearing contact lenses
Storage Conditions
Keep in a dry place away from light and heat, Keep out of the reach of children