Ostelac 10 mg (Tablet)
Unit Price: ৳ 10.00 (30's pack: ৳ 300.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ketorolac tromethamine |
| Company | Supreme pharmaceutical ltd |
Indications
- Short-term management of post-operative pain
- Relief of pain, inflammation, and light sensitivity after ocular surgery
- Reduction of eye inflammation or redness caused by seasonal allergies
Description
- Belongs to pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drugs (NSAID)
- Inhibits synthesis of prostaglandins
- Peripherally acting analgesic
- Linear pharmacokinetic property
- Metabolized in liver
- Excreted in urine
Pharmacology
- Potent analgesic of the non-steroidal anti-inflammatory drugs (NSAIDs)
- Inhibits cyclooxygenase enzyme system
- Minimal anti-inflammatory effect at analgesic dose
Dosage & Administration
- Tablet: Recommended dose is 10 mg every 4-6 hours
- Injection: Single or multiple doses for management of acute pain
- Eye Drops: 1 drop in each eye 4 times daily
Interaction
- Other NSAIDs or aspirin increase side effects
- Anti-coagulants enhance anti-coagulant effect
- Beta Blocker reduces anti-hypertensive effect
- ACE Inhibitors increase risk of renal impairment
- Methotrexate enhances toxicity
Contraindications
- Hypersensitivity to drug or other NSAIDs
- Children under 16 years of age
- Prophylactic analgesic before surgery
Side Effects
- Nausea
- Vomiting
- Gastro-intestinal bleeding
- Melena
- Peptic ulcer
- Pancreatitis
- Anxiety
- Drowsiness
- Headache
- Excessive thirst
- Fatigue
- Bradycardia
- Hypertension
- Palpitation
- Chest pain
- Infertility in female
- Pulmonary edema
Pregnancy & Lactation
- FDA Pregnancy category C
- Avoid in pregnancy and lactation unless benefits outweigh risks
Precautions & Warnings
- Exercised caution in patients over 65 years
- Caution in patients with peptic ulcer, gastrointestinal bleeding, asthma, and liver dysfunction
- Discontinue use for corneal epithelial breakdown in eye drops
- Do not administer while wearing contact lenses
Therapeutic Class
- Rheumatoid Arthritis Drugs
- Non-Opioid Analgesics
Storage Conditions
- Keep in dry place away from light and heat
- Keep out of reach of children